IHC (Immunohiostchemistry)
(Immunohistochemistry of ADRM1 in human spleen tissue with ADRM1 antibody at 5 μg/mL.)
Rabbit ADRM1 Polyclonal Antibody | anti-ADRM1 antibody
ADRM1 Antibody
Gene Names
ADRM1; ARM1; ARM-1; GP110
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
ADRM1 antibody is affinity chromatography purified via peptide column.
Synonyms
ADRM1, Antibody; ADRM1 Antibody; Adhesion regulating molecule 1; ARM1; Gp110; hRpn13; Proteasomal ubiquitin receptor ADRM1; Proteasome regulatory particle non-ATPase 13; Rpn13; adhesion regulating molecule 1; anti-ADRM1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ADRM1 antibody is human, mouse and rat reactive. At least two isoforms of ADRM1 are know to exist; this antibody will detect both isoforms.
Purity/Purification
ADRM1 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
407
Applicable Applications for anti-ADRM1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
ADRM1 antibody was raised against a 19 amino acid peptide near the center of human ADRM1.
Buffer
ADRM1 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ADRM1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IHC (Immunohiostchemistry)
(Immunohistochemistry of ADRM1 in human spleen tissue with ADRM1 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of ADRM1 in human spleen tissue with ADRM1 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of ADRM1 in EL cell lysate with ADRM1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of ADRM1 in EL cell lysate with ADRM1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-ADRM1 antibody
The adhesion-regulating molecule 1 (ADRM1) is thought to be involved in protein recruitment and cell adhesion and functions as a proteasomal ubiquitin receptor (1). ADRM1 promotes the activity of UCH-L5 and plays a role in lymphocyte homing. The carboxy-terminal domain of mammalian ADRM1 serves to bind and enhance the isopeptidase activity of UCHL5/UCH37, perhaps serving as a mechanism to accelerate ubiquitin chain disassembly (2,3). ADRM1 expression is induced by IFN-gamma in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis (4,5).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 45 kDa
Observed: 48 kDa
Observed: 48 kDa
NCBI Official Full Name
proteasomal ubiquitin receptor ADRM1 isoform 1
NCBI Official Synonym Full Names
adhesion regulating molecule 1
NCBI Official Symbol
ADRM1
NCBI Official Synonym Symbols
ARM1; ARM-1; GP110
NCBI Protein Information
proteasomal ubiquitin receptor ADRM1; rpn13 homolog; M(r) 110,000 surface antigen; 110 kDa cell membrane glycoprotein; proteasome regulatory particle non-ATPase 13
UniProt Protein Name
Proteasomal ubiquitin receptor ADRM1
UniProt Gene Name
ADRM1
UniProt Synonym Gene Names
GP110; Gp110; ARM-1; hRpn13
UniProt Entry Name
ADRM1_HUMAN
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Product Notes
The ADRM1 adrm1 (Catalog #AAA40582) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADRM1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ADRM1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ADRM1 adrm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADRM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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