IHC (Immunohiostchemistry)
(AFG3L2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AFG3L2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit AFG3L2 Polyclonal Antibody | anti-AFG3L2 antibody
AFG3L2 Antibody (N-term)
Gene Names
AFG3L2; SCA28; SPAX5
Reactivity
HumanPredicted Reactivity: Bovine, Mouse
Applications
Immunohistochemistry, ELISA, Western Blot
Synonyms
AFG3L2, Antibody; AFG3L2 Antibody (N-term); AFG3-like protein 2; 3424-; Paraplegin-like protein; AFG3L2; anti-AFG3L2 antibody
Host
Rabbit
Reactivity
Human
Predicted Reactivity: Bovine, Mouse
Predicted Reactivity: Bovine, Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This AFG3L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the N-terminal region of human AFG3L2.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
52-80
Sequence Length
797
Applicable Applications for anti-AFG3L2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Cellular Location
Mitochondrian. Mitochondrian inner membrane. ECO:0000250|UniProtKB:Q8JZQ2};Multi-pass membrane protein
Antigen Region
52-80
Tissue Location
Ubiquitous. Highly expressed in thecerebellar Purkinje cells.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(AFG3L2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AFG3L2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(AFG3L2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AFG3L2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(AFG3L2 Antibody (N-term) western blot analysis in MDA-MB453,MCF-7,Jurkat cell line lysates (35ug/lane).This demonstrates the AFG3L2 antibody detected the AFG3L2 protein (arrow).)
WB (Western Blot)
(AFG3L2 Antibody (N-term) western blot analysis in MDA-MB453,MCF-7,Jurkat cell line lysates (35ug/lane).This demonstrates the AFG3L2 antibody detected the AFG3L2 protein (arrow).)
Related Product Information for anti-AFG3L2 antibody
This gene encodes a protein localized in mitochondria and
closely related to paraplegin. The paraplegin gene is responsible
for an autosomal recessive form of hereditary spastic paraplegia.
This gene is a candidate gene for other hereditary spastic
paraplegias or neurodegenerative disorders.
closely related to paraplegin. The paraplegin gene is responsible
for an autosomal recessive form of hereditary spastic paraplegia.
This gene is a candidate gene for other hereditary spastic
paraplegias or neurodegenerative disorders.
Product Categories/Family for anti-AFG3L2 antibody
References
Edener, U., et al. Eur. J. Hum. Genet. 18(8):965-968(2010)
Di Bella, D., et al. Nat. Genet. 42(4):313-321(2010)
Augustin, S., et al. Mol. Cell 35(5):574-585(2009)
Mariotti, C., et al. Cerebellum 7(2):184-188(2008)
Cagnoli, C., et al. Brain 129 (PT 1), 235-242 (2006) :
Di Bella, D., et al. Nat. Genet. 42(4):313-321(2010)
Augustin, S., et al. Mol. Cell 35(5):574-585(2009)
Mariotti, C., et al. Cerebellum 7(2):184-188(2008)
Cagnoli, C., et al. Brain 129 (PT 1), 235-242 (2006) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
88584
NCBI Official Full Name
AFG3-like protein 2
NCBI Official Synonym Full Names
AFG3-like AAA ATPase 2
NCBI Official Symbol
AFG3L2
NCBI Official Synonym Symbols
SCA28; SPAX5
NCBI Protein Information
AFG3-like protein 2
UniProt Protein Name
AFG3-like protein 2
UniProt Gene Name
AFG3L2
UniProt Entry Name
AFG32_HUMAN
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Product Notes
The AFG3L2 afg3l2 (Catalog #AAA286084) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 52-80. The AFG3L2 Antibody (N-term) reacts with Human Predicted Reactivity: Bovine, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AFG3L2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the AFG3L2 afg3l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AFG3L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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