FCM/FACS (Flow Cytometry)
(AHCY Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit AHCY Polyclonal Antibody | anti-AHCY antibody
AHCY Antibody (N-term)
Gene Names
AHCY; SAHH; adoHcyase
Reactivity
Mouse (Predicted Reactivity: Bovine, Monkey, Pig)
Applications
Western Blot, Flow Cytometry, Functional Assay, Immunohistochemistry, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
AHCY, Antibody; AHCY Antibody (N-term); Adenosylhomocysteinase; AdoHcyase; S-adenosyl-L-homocysteine hydrolase; AHCY; SAHH; anti-AHCY antibody
Host
Rabbit
Reactivity
Mouse (Predicted Reactivity: Bovine, Monkey, Pig)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This AHCY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-110 amino acids from the N-terminal region of human AHCY.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
79-110
Sequence Length
404
Applicable Applications for anti-AHCY antibody
WB (Western Blot), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(AHCY Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(AHCY Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
IHC (Immunohiostchemistry)
(AHCY Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AHCY Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(AHCY Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AHCY Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(AHCY Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the AHCY antibody detected the AHCY protein (arrow).)
WB (Western Blot)
(AHCY Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the AHCY antibody detected the AHCY protein (arrow).)
Related Product Information for anti-AHCY antibody
S-adenosylhomocysteine hydrolase belongs to the
adenosylhomocysteinase family. It catalyzes the reversible
hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado)
and L-homocysteine (Hcy). Thus, it regulates the intracellular
S-adenosylhomocysteine (SAH) concentration thought to be important
for transmethylation reactions. Deficiency in this protein is one
of the different causes of hypermethioninemia. Alternatively
spliced transcript variants encoding different isoforms have been
found for this gene.
adenosylhomocysteinase family. It catalyzes the reversible
hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado)
and L-homocysteine (Hcy). Thus, it regulates the intracellular
S-adenosylhomocysteine (SAH) concentration thought to be important
for transmethylation reactions. Deficiency in this protein is one
of the different causes of hypermethioninemia. Alternatively
spliced transcript variants encoding different isoforms have been
found for this gene.
Product Categories/Family for anti-AHCY antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Gass, N., et al. J Affect Disord 126 (1-2), 134-139 (2010) :
Giusti, B., et al. Thromb. Haemost. 104(2):231-242(2010)
Levine, A.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1812-1821(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Gass, N., et al. J Affect Disord 126 (1-2), 134-139 (2010) :
Giusti, B., et al. Thromb. Haemost. 104(2):231-242(2010)
Levine, A.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1812-1821(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47716
NCBI Official Full Name
adenosylhomocysteinase isoform 1
NCBI Official Synonym Full Names
adenosylhomocysteinase
NCBI Official Symbol
AHCY
NCBI Official Synonym Symbols
SAHH; adoHcyase
NCBI Protein Information
adenosylhomocysteinase
UniProt Protein Name
Adenosylhomocysteinase
UniProt Gene Name
AHCY
UniProt Synonym Gene Names
SAHH; AdoHcyase
UniProt Entry Name
SAHH_HUMAN
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Product Notes
The AHCY ahcy (Catalog #AAA284481) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 79-110. The AHCY Antibody (N-term) reacts with Mouse (Predicted Reactivity: Bovine, Monkey, Pig) and may cross-react with other species as described in the data sheet. AAA Biotech's AHCY can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the AHCY ahcy for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AHCY, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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