IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/60.)
Rabbit anti-Human AIM2 Polyclonal Antibody | anti-AIM2 antibody
AIM2 Antibody
Gene Names
AIM2; PYHIN4
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
AIM2, Antibody; AIM2 Antibody; PYHIN4; anti-AIM2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total AIM2 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
3.4 mg/ml (varies by lot)
Sequence Length
343
Applicable Applications for anti-AIM2 antibody
IHC (Immunohistochemistry)
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to a region derived from internal residues of human absent in melanoma 2
Target Name
AIM2
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/60.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/60.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/60.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/60.)
Related Product Information for anti-AIM2 antibody
Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN- , AIM2 is thought to act as a tumor suppressor by repressing NF B transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
Product Categories/Family for anti-AIM2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,954 Da
NCBI Official Full Name
interferon-inducible protein AIM2
NCBI Official Synonym Full Names
absent in melanoma 2
NCBI Official Symbol
AIM2
NCBI Official Synonym Symbols
PYHIN4
NCBI Protein Information
interferon-inducible protein AIM2
UniProt Protein Name
Interferon-inducible protein AIM2
UniProt Gene Name
AIM2
UniProt Entry Name
AIM2_HUMAN
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Product Notes
The AIM2 aim2 (Catalog #AAA304101) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AIM2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AIM2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the AIM2 aim2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AIM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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