IHC (Immunohiostchemistry)
(AAA327690 at 1/100 staining Mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
Rabbit anti-Human, Mouse AKAP6 Polyclonal Antibody | anti-AKAP6 antibody
AKAP6 Antibody
Gene Names
AKAP6; ADAP6; PRKA6; mAKAP; ADAP100; AKAP100
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
AKAP6, Antibody; AKAP6 Antibody; A kinase (PRKA) anchor protein 6; A kinase anchor protein 100; A kinase anchor protein 100 kDa; A kinase anchor protein 6; ADAP 100; ADAP 6; ADAP100; ADAP6; AKAP 100; AKAP 6; AKAP100; Human A kinase anchor protein AKAP100; KIAA0311; mAKAP; PRKA 6; PRKA6; Protein kinase A anchoring protein 6; anti-AKAP6 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
AKAP6 antibody detects endogenous levels of total AKAP6
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
2319
Applicable Applications for anti-AKAP6 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human AKAP6
Subcellular Location
Sarcoplasmic reticulum and nuclear membrane in heart muscle.
Tissue Specificity
Highly expressed in cardiac and skeletal muscle, followed by brain.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
IHC (Immunohiostchemistry)
(AAA327690 at 1/100 staining Mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
IHC (Immunohiostchemistry)
(AAA327690 at 1/100 staining Mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
WB (Western Blot)
(Western blot analysis of AKAP6 using HuvEc whole cell lysates)
WB (Western Blot)
(Western blot analysis of AKAP6 using HuvEc whole cell lysates)
Related Product Information for anti-AKAP6 antibody
Function: Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes.
Subunit Structure: Interacts with RII subunit of PKA, phosphatase 2B (calcineurin) and AKAP79. Interacts with SYNPO2.
Similarity: RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.
Subunit Structure: Interacts with RII subunit of PKA, phosphatase 2B (calcineurin) and AKAP79. Interacts with SYNPO2.
Similarity: RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 257 kDa
Predicted: 257 kDa
Predicted: 257 kDa
NCBI Official Full Name
A-kinase anchor protein 6
NCBI Official Synonym Full Names
A-kinase anchoring protein 6
NCBI Official Symbol
AKAP6
NCBI Official Synonym Symbols
ADAP6; PRKA6; mAKAP; ADAP100; AKAP100
NCBI Protein Information
A-kinase anchor protein 6
UniProt Protein Name
A-kinase anchor protein 6
UniProt Gene Name
AKAP6
UniProt Synonym Gene Names
AKAP100; KIAA0311; AKAP-6; AKAP 100; PRKA6
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Product Notes
The AKAP6 akap6 (Catalog #AAA327690) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AKAP6 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AKAP6 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the AKAP6 akap6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AKAP6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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