IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human kideny tissue reacted with ALDH1A3 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Rabbit anti-Human, mouse ALDH1A3 Polyclonal Antibody | anti-ALDH1A3 antibody
ALDH1A3 Antibody (N-term)
Gene Names
ALDH1A3; ALDH6; MCOP8; RALDH3; ALDH1A6
Reactivity
Human, mouse
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ALDH1A3, Antibody; ALDH1A3 Antibody (N-term); Aldehyde dehydrogenase family 1 member A3; Aldehyde dehydrogenase 6; Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; ALDH1A3; ALDH6; anti-ALDH1A3 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ALDH1A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human ALDH1A3.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
24-51
Sequence Length
512
Applicable Applications for anti-ALDH1A3 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Crown Antibody
Yes
Antigen Source
HUMAN
Function
Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity).
Cellular Location
Cytoplasm
Tissue Location
Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human kideny tissue reacted with ALDH1A3 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human kideny tissue reacted with ALDH1A3 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(ALDH1A3 Antibody (N-term) western blot analysis in 293,Y79 cell line lysates (35ug/lane).This demonstrates the ALDH1A3 antibody detected the ALDH1A3 protein (arrow).)
WB (Western Blot)
(ALDH1A3 Antibody (N-term) western blot analysis in 293,Y79 cell line lysates (35ug/lane).This demonstrates the ALDH1A3 antibody detected the ALDH1A3 protein (arrow).)
Related Product Information for anti-ALDH1A3 antibody
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme ALDH1A3 uses retinal as a substrate, either in a free or cellular retinol-binding protein form.
Product Categories/Family for anti-ALDH1A3 antibody
References
Rexer,B.N., Cancer Res. 61 (19), 7065-7070 (2001)
Yoshida,A., Eur. J. Biochem. 251 (3), 549-557 (1998)
Yoshida,A., Eur. J. Biochem. 251 (3), 549-557 (1998)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56108
NCBI Official Full Name
aldehyde dehydrogenase family 1 member A3 isoform 1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family, member A3
NCBI Official Symbol
ALDH1A3
NCBI Official Synonym Symbols
ALDH6; MCOP8; RALDH3; ALDH1A6
NCBI Protein Information
aldehyde dehydrogenase family 1 member A3
UniProt Protein Name
Aldehyde dehydrogenase family 1 member A3
UniProt Gene Name
ALDH1A3
UniProt Synonym Gene Names
ALDH6; RALDH-3; RalDH3
UniProt Entry Name
AL1A3_HUMAN
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Product Notes
The ALDH1A3 aldh1a3 (Catalog #AAA289570) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 24-51. The ALDH1A3 Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ALDH1A3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the ALDH1A3 aldh1a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALDH1A3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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