ICC (Immunocytochemistry)
(Immunocytochemistry of ALSFTD in A-20 cells with ALSFTD antibody at 10 μg/ml.)
Rabbit ALSFTD Polyclonal Antibody | anti-ALSFTD antibody
ALSFTD Antibody
Gene Names
C9orf72; ALSFTD; FTDALS; FTDALS1
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column.
Synonyms
ALSFTD, Antibody; ALSFTD Antibody; Amyotrophic lateral sclerosis with frontotemporal dementia, chromosome 9 open reading frame 72, C9orf72; anti-ALSFTD antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ALSFTD antibody is human, mouse and rat reactive. At least two isoforms are known to exist.
Purity/Purification
Affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
481
Applicable Applications for anti-ALSFTD antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen
ALSFTD antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ALSFTD.
Buffer
Supplied in PBS containing 0.02% sodium azide.
Positive Control 1
A20 Cell Lysate
Conjugate
Unconjugated
Preparation and Storage
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
ICC (Immunocytochemistry)
(Immunocytochemistry of ALSFTD in A-20 cells with ALSFTD antibody at 10 μg/ml.)
ICC (Immunocytochemistry)
(Immunocytochemistry of ALSFTD in A-20 cells with ALSFTD antibody at 10 μg/ml.)
WB (Western Blot)
(Western blot analysis of ALSFTD in HeLa cell lysate with ALSFTD antibody at 1 μg/ml.)
WB (Western Blot)
(Western blot analysis of ALSFTD in HeLa cell lysate with ALSFTD antibody at 1 μg/ml.)
Related Product Information for anti-ALSFTD antibody
ALSFTD (C9orf72) is considered to play a role in gender determination (1). Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2). Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3,4).
Product Categories/Family for anti-ALSFTD antibody
References
Takada LT and Sha SJ. Neuropsychiatric features of C9orf72-associated behavioral variant frontotemporal dementia and frontotemporal dementia with motor neuron disease. Alzheimers Res. Ther. 2012; 4:38. Coon EA, Whitwell JL, Parisi JE, et al. Right temporal variant frontotemporal dementia with motor neuron disease. J. Clin. Neurosci. 2012; 19:85-91. Snowden JS, Rollinson S, Thompson JC, et al. Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations. Brain 2012; 135:693-708. Wen X, Tan W, Westergard T, et al. Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death. Neuron 2014; 84:1213-25.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 53 kDa
Observed: 52 kDa
Observed: 52 kDa
NCBI Official Full Name
protein C9orf72 isoform a
NCBI Official Synonym Full Names
chromosome 9 open reading frame 72
NCBI Official Symbol
C9orf72
NCBI Official Synonym Symbols
ALSFTD; FTDALS; FTDALS1
NCBI Protein Information
protein C9orf72
UniProt Protein Name
Protein C9orf72
UniProt Gene Name
C9orf72
UniProt Entry Name
CI072_HUMAN
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Product Notes
The ALSFTD c9orf72 (Catalog #AAA40842) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ALSFTD Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ALSFTD can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ALSFTD c9orf72 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALSFTD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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