FCM/FACS (Flow Cytometry)
(ALX4 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit ALX4 Polyclonal Antibody | anti-ALX4 antibody
ALX4 Antibody (Center)
Gene Names
ALX4; CRS5; FND2
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ALX4, Antibody; ALX4 Antibody (Center); Homeobox protein aristaless-like 4; ALX4; KIAA1788; anti-ALX4 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ALX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-275 amino acids from the Central region of human ALX4.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.44 (varies by lot)
Sequence Positions
249-275
Sequence Length
411
Applicable Applications for anti-ALX4 antibody
FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(ALX4 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(ALX4 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
WB (Western Blot)
(ALX4 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the ALX4 antibody detected the ALX4 protein (arrow).)
WB (Western Blot)
(ALX4 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the ALX4 antibody detected the ALX4 protein (arrow).)
Related Product Information for anti-ALX4 antibody
This gene encodes a paired-like homeodomain transcription
factor expressed in the mesenchyme of developing bones, limbs,
hair, teeth, and mammary tissue. Mutations in this gene cause
parietal foramina 2 (PFM2); an autosomal dominant disease
characterized by deficient ossification of the parietal bones.
Mutations in this gene also cause a form of frontonasal dysplasia
with alopecia and hypogonadism; suggesting a role for this gene in
craniofacial development, mesenchymal-epithelial communication, and
hair follicle development. Deletion of a segment of chromosome 11
containing this gene, del(11)(p11p12), causes Potocki-Shaffer
syndrome (PSS); a syndrome characterized by craniofacial anomalies,
mental retardation, multiple exostoses, and genital abnormalities
in males. In mouse, this gene has been shown to use dual
translation initiation sites located 16 codons apart. [provided by
RefSeq].
factor expressed in the mesenchyme of developing bones, limbs,
hair, teeth, and mammary tissue. Mutations in this gene cause
parietal foramina 2 (PFM2); an autosomal dominant disease
characterized by deficient ossification of the parietal bones.
Mutations in this gene also cause a form of frontonasal dysplasia
with alopecia and hypogonadism; suggesting a role for this gene in
craniofacial development, mesenchymal-epithelial communication, and
hair follicle development. Deletion of a segment of chromosome 11
containing this gene, del(11)(p11p12), causes Potocki-Shaffer
syndrome (PSS); a syndrome characterized by craniofacial anomalies,
mental retardation, multiple exostoses, and genital abnormalities
in males. In mouse, this gene has been shown to use dual
translation initiation sites located 16 codons apart. [provided by
RefSeq].
References
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Tanzer, M., et al. PLoS ONE 5 (2), E9061 (2010) :
Kayserili, H., et al. Hum. Mol. Genet. 18(22):4357-4366(2009)
Chang, H., et al. J. Clin. Pathol. 62(10):908-914(2009)
Drenos, F., et al. Hum. Mol. Genet. 18(12):2305-2316(2009)
Tanzer, M., et al. PLoS ONE 5 (2), E9061 (2010) :
Kayserili, H., et al. Hum. Mol. Genet. 18(22):4357-4366(2009)
Chang, H., et al. J. Clin. Pathol. 62(10):908-914(2009)
Drenos, F., et al. Hum. Mol. Genet. 18(12):2305-2316(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44241
NCBI Official Full Name
homeobox protein aristaless-like 4
NCBI Official Synonym Full Names
ALX homeobox 4
NCBI Official Symbol
ALX4
NCBI Official Synonym Symbols
CRS5; FND2
NCBI Protein Information
homeobox protein aristaless-like 4
UniProt Protein Name
Homeobox protein aristaless-like 4
UniProt Gene Name
ALX4
UniProt Synonym Gene Names
KIAA1788
UniProt Entry Name
ALX4_HUMAN
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Product Notes
The ALX4 alx4 (Catalog #AAA290373) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 249-275. The ALX4 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's ALX4 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the ALX4 alx4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALX4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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