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product-image-AAA321811_WB13.jpg WB (Western Blot) (Western blot analysis of ANG 2 Antibody expression in Rat kidney tissue lysates.The lane on the left is treated with the antigen-specific peptide.)

Rabbit ANG 2 Polyclonal Antibody | anti-ANGPT2 antibody

ANG 2 Antibody

Gene Names
ANGPT2; ANG2; AGPT2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
ANG 2, Antibody; ANG 2 Antibody; AGPT 2; Agpt2; ANG 2; ANG-2; ANG2; Angiopoietin 2a; Angiopoietin 2B; Angiopoietin-2; Angiopoietin2; ANGP2_HUMAN; ANGPT 2; Angpt2; Tie2 ligand; anti-ANGPT2 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ANG 2 antibody detects endogenous levels of total ANG 2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
495
Applicable Applications for anti-ANGPT2 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human ANG 2, corresponding to a region within N-terminal amino acids.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

WB (Western Blot)

(Western blot analysis of ANG 2 Antibody expression in Rat kidney tissue lysates.The lane on the left is treated with the antigen-specific peptide.)

product-image-AAA321811_WB13.jpg WB (Western Blot) (Western blot analysis of ANG 2 Antibody expression in Rat kidney tissue lysates.The lane on the left is treated with the antigen-specific peptide.)

IHC (Immunohistochemistry)

(AAA321811 at 1/100 staining human brain tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)

product-image-AAA321811_IHC15.jpg IHC (Immunohistochemistry) (AAA321811 at 1/100 staining human brain tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
Related Product Information for anti-ANGPT2 antibody
Description: Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression.

Similarity: The Fibrinogen C-terminal domain mediates interaction with the TEK/TIE2 receptor.
References
Chen W, Chen J, Xu M, Zhong Z, Zhang Q, Yang W, Huang G; Journal: Biol Reprod. Electroacupuncture facilitates implantation by enhancing endometrial angiogenesis in a rat model of ovarian hyperstimulation. Wu X, Hu Z, Yin Y, Li Y, Zhang T; Journal: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. [Dose and timing of normal saline resuscitation on endothelial glycocalyx in early septic shock].

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
285
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57 kDa
NCBI Official Full Name
angiopoietin-2 isoform b
NCBI Official Synonym Full Names
angiopoietin 2
NCBI Official Symbol
ANGPT2
NCBI Official Synonym Symbols
ANG2; AGPT2
NCBI Protein Information
angiopoietin-2
UniProt Protein Name
Angiopoietin-2
UniProt Gene Name
ANGPT2
UniProt Synonym Gene Names
ANG-2

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Product Notes

The ANGPT2 angpt2 (Catalog #AAA321811) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ANG 2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ANG 2 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ANGPT2 angpt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ANG 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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