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product-image-AAA46050_IHC8.jpg IHC (Immunohistochemistry) (Anti-ACE Picoband antibody, AAA46050-5.JPGIHC(P): Rat Lung Tissue)

Rabbit Angiotensin-converting enzyme Polyclonal Antibody | anti-ACE antibody

Anti-ACE Antibody

Gene Names
ACE; DCP; ICH; ACE1; DCP1; CD143; MVCD3
Reactivity
Human, Mouse, Rat. No cross reactivity with other proteins.
Applications
Immunohistochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Angiotensin-converting enzyme, Antibody; Anti-ACE Antibody; ACE 1 antibody; ACE antibody; ACE T antibody; ACE_HUMAN antibody; ACE1 antibody; Angiotensin converting enzyme somatic isoform antibody; Angiotensin converting enzyme testis specific isoform antibody; Angiotensin I converting enzyme antibody; Angiotensin I converting enzyme 1 antibody; Angiotensin I converting enzyme peptidyl dipeptidase A 1 antibody; Angiotensin-converting enzyme antibody; Carboxycathepsin antibody; CD 143 antibody; CD143 antibody; CD143 antigen antibody; DCP 1 antibody; DCP antibody; DCP1 antibody; Dipeptidyl carboxypeptidase 1 antibody; Dipeptidyl carboxypeptidase I antibody; Kininase II antibody; MGC26566 antibody; MVCD3 antibody; Peptidase P antibody; Peptidyl dipeptidase A antibody; soluble form antibody; Testicular ECA antibody; angiotensin I converting enzyme; anti-ACE antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat. No cross reactivity with other proteins.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
1306
Applicable Applications for anti-ACE antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
E.coli-derived human ACE recombinant protein (Position: K651-Y864). Human ACE shares 73% and 76% amino acid (aa) sequences identity with mouse and rat ACE, respectively.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

IHC (Immunohistochemistry)

(Anti-ACE Picoband antibody, AAA46050-5.JPGIHC(P): Rat Lung Tissue)

product-image-AAA46050_IHC8.jpg IHC (Immunohistochemistry) (Anti-ACE Picoband antibody, AAA46050-5.JPGIHC(P): Rat Lung Tissue)

IHC (Immunohistochemistry)

(Anti-ACE Picoband antibody, AAA46050-4.JPGIHC(P): Rat Lung Tissue)

product-image-AAA46050_IHC10.jpg IHC (Immunohistochemistry) (Anti-ACE Picoband antibody, AAA46050-4.JPGIHC(P): Rat Lung Tissue)

IHC (Immunohistochemisry)

(Anti-ACE Picoband antibody, AAA46050-3.JPGIHC(P): Mouse Lung Tissue)

product-image-AAA46050_IHC11.jpg IHC (Immunohistochemisry) (Anti-ACE Picoband antibody, AAA46050-3.JPGIHC(P): Mouse Lung Tissue)

IHC (Immunohiostchemistry)

(Anti-ACE Picoband antibody, AAA46050-2.JPGIHC(P): Human Placenta Tissue)

product-image-AAA46050_IHC13.jpg IHC (Immunohiostchemistry) (Anti-ACE Picoband antibody, AAA46050-2.JPGIHC(P): Human Placenta Tissue)

Application Data

(Anti-ACE Picoband antibody, AAA46050-1.jpgAll lanes: Anti ACE (AAA46050) at 0.5ug/mlWB: Recombinant Human ACE Protein 0.5ngPredicted bind size: 47KDObserved bind size: 47KD)

product-image-AAA46050_AD15.jpg Application Data (Anti-ACE Picoband antibody, AAA46050-1.jpgAll lanes: Anti ACE (AAA46050) at 0.5ug/mlWB: Recombinant Human ACE Protein 0.5ngPredicted bind size: 47KDObserved bind size: 47KD)
Related Product Information for anti-ACE antibody
Description: Rabbit IgG polyclonal antibody for Angiotensin-converting enzyme(ACE) detection. Tested with WB, IHC-P, IHC-F in Human;Mouse;Rat.
Background: Angiotensin-converting enzyme (ACE), an exopeptidase, is a circulating enzyme that participates in the body's renin-angiotensin system(RAS), which mediates extracellular volume (i.e. that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. It is secreted by pulmonary and renal endothelial cells and catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II. Using a DNA marker at the growth hormone gene locus, which they characterized as 'extremely polymorphic' and which showed no recombination with ACE, ACE was mapped to 17q22-q24, consistent with the in situ hybridization mapping to 17q23. ACE, or kininase II, is a dipeptidyl carboxypeptidase that plays an important role in blood pressure regulation and electrolyte balance by hydrolyzing angiotensin I into angiotensin II, a potent vasopressor, and aldosterone-stimulating peptide. The enzyme is also able to inactivate bradykinin, a potent vasodilator.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
78,694 Da
NCBI Official Full Name
angiotensin-converting enzyme isoform 1
NCBI Official Synonym Full Names
angiotensin I converting enzyme
NCBI Official Symbol
ACE
NCBI Official Synonym Symbols
DCP; ICH; ACE1; DCP1; CD143; MVCD3
NCBI Protein Information
angiotensin-converting enzyme; kininase II; peptidase P; CD143 antigen; testicular ECA; carboxycathepsin; dipeptidyl carboxypeptidase 1; dipeptidyl carboxypeptidase I; angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript
UniProt Protein Name
Angiotensin-converting enzyme
UniProt Gene Name
ACE
UniProt Synonym Gene Names
DCP; DCP1; ACE
UniProt Entry Name
ACE_HUMAN

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Product Notes

The ACE ace (Catalog #AAA46050) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ACE Antibody reacts with Human, Mouse, Rat. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Angiotensin-converting enzyme can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ACE ace for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Angiotensin-converting enzyme, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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