Rabbit anti-Bacteria Anthrax Protective Polyclonal Antibody | anti-pxo1_110 antibody
Anthrax Protective Antigen Antibody
Reactivity
Bacteria
Applications
ELISA
Purity
Anthrax Protective Antigen Antibody is affinity chromatography purified via peptide column.
Synonyms
Anthrax Protective, Antibody; Anthrax Protective Antigen Antibody; Anthrax Protective Antigen; pag; pXO1-110; BXA0164; GBAA_pXO1_0164; Protective antigen; Anthrax toxins translocating protein; PA; anti-pxo1_110 antibody
Host
Rabbit
Reactivity
Bacteria
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Anthrax Protective Antigen Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
764
Applicable Applications for anti-pxo1_110 antibody
ELISA
Conjugate
Unconjugated
Immunogen
Anthrax protective antigen antibody was raised against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of the Anthrax protective antigen protein.
The immunogen is located within amino acids 600-650 of Anthrax Protective Antigen.
The immunogen is located within amino acids 600-650 of Anthrax Protective Antigen.
Buffer
Anthrax Protective Antigen Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Anthrax Protective Antigen antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Related Product Information for anti-pxo1_110 antibody
Anthrax Protective Antigen Antibody: Anthrax infection is initiated by the inhalation, ingestion, or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF), and edema factor (EF). PA binds to two related proteins on the cell surface; these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) and capillary morphogenesis protein 2 (CMG2), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin-like protease. The bound fragment binds both LF and EF; the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm. These toxins are usually sufficient to cause rapid cell death, and often the death of the organism.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
protective antigen
NCBI Official Symbol
pxo1_110
NCBI Protein Information
pXO1-110
UniProt Protein Name
Protective antigen
UniProt Gene Name
pagA
UniProt Synonym Gene Names
pag; PA; PA83; PA20; PA63
UniProt Entry Name
PAG_BACAN
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Product Notes
The pxo1_110 paga (Catalog #AAA39793) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anthrax Protective Antigen Antibody reacts with Bacteria and may cross-react with other species as described in the data sheet. AAA Biotech's Anthrax Protective can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the pxo1_110 paga for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Anthrax Protective, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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