IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ANTXR1 Antibody (Y382) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Rabbit ANTXR1 Polyclonal Antibody | anti-ANTXR1 antibody
ANTXR1 Antibody (Y382)
Gene Names
ANTXR1; ATR; GAPO; TEM8
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ANTXR1, Antibody; ANTXR1 Antibody (Y382); Anthrax toxin receptor 1; Tumor endothelial marker 8; ANTXR1; ATR; TEM8; anti-ANTXR1 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ANTXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-386 amino acids from human ANTXR1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
358-386
Sequence Length
358
Applicable Applications for anti-ANTXR1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ANTXR1 Antibody (Y382) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ANTXR1 Antibody (Y382) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of anti-ANTXR1 Antibody (Y382) in Hela cell line lysates (35ug/lane). ANTXR1 (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of anti-ANTXR1 Antibody (Y382) in Hela cell line lysates (35ug/lane). ANTXR1 (arrow) was detected using the purified Pab.)
Related Product Information for anti-ANTXR1 antibody
ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Product Categories/Family for anti-ANTXR1 antibody
References
Werner,E., J. Biol. Chem. 281 (32), 23227-23236 (2006)
Wei,W., Cell 124 (6), 1141-1154 (2006)
Rainey,G.J., Proc. Natl. Acad. Sci. U.S.A. 102 (37), 13278-13283 (2005)
Wei,W., Cell 124 (6), 1141-1154 (2006)
Rainey,G.J., Proc. Natl. Acad. Sci. U.S.A. 102 (37), 13278-13283 (2005)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
62789
NCBI Official Full Name
anthrax toxin receptor 1 isoform 3
NCBI Official Synonym Full Names
anthrax toxin receptor 1
NCBI Official Symbol
ANTXR1
NCBI Official Synonym Symbols
ATR; GAPO; TEM8
NCBI Protein Information
anthrax toxin receptor 1
UniProt Protein Name
Anthrax toxin receptor 1
UniProt Gene Name
ANTXR1
UniProt Synonym Gene Names
ATR; TEM8
UniProt Entry Name
ANTR1_HUMAN
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Product Notes
The ANTXR1 antxr1 (Catalog #AAA283790) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 358-386. The ANTXR1 Antibody (Y382) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's ANTXR1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the ANTXR1 antxr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ANTXR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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