WB (Western Blot)
(Western blot analysis of extracts from Rat brain, using AP3D1 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit AP3D1 Polyclonal Antibody | anti-AP3D1 antibody
AP3D1 Antibody
Gene Names
AP3D1; ADTD; HPS10; hBLVR
Reactivity
Human, Mouse, RatPredicted: Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
AP3D1, Antibody; AP3D1 Antibody; Adapter-related protein complex 3 subunit delta-1; adaptor-related protein complex 3, delta 1 subunit; ADTD; AP 3 complex delta subunit; AP-3 complex subunit delta; AP-3 complex subunit delta-1; ap3d1; AP3D1_HUMAN; Delta 1 subunit of adaptor-related protein complex 3; Delta Adaptin; Delta-adaptin; hBLVR; Subunit of putative vesicle coat adaptor complex AP 3; anti-AP3D1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
Predicted: Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
Clonality
Polyclonal
Isotype
IgG
Specificity
AP3D1 Antibody detects endogenous levels of AP3D1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1153
Applicable Applications for anti-AP3D1 antibody
WB (Western Blot)
Immunogen
A synthesized peptide derived from human AP3D1.
Tissue Specificity
Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Golgi Apparatus
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of extracts from Rat brain, using AP3D1 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Rat brain, using AP3D1 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from HeLa cells, using AP3D1 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from HeLa cells, using AP3D1 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-AP3D1 antibody
Description: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation (PubMed:26744459). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity).
Subunit Structure: AP-3 associates with the BLOC-1 complex (By similarity). Adaptor protein complex 3 (AP-3) is a heterotetramer composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin (mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2) (By similarity). Interacts with SLC30A2 (PubMed:25808614).
Similarity: Belongs to the adaptor complexes large subunit family.
Subunit Structure: AP-3 associates with the BLOC-1 complex (By similarity). Adaptor protein complex 3 (AP-3) is a heterotetramer composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin (mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2) (By similarity). Interacts with SLC30A2 (PubMed:25808614).
Similarity: Belongs to the adaptor complexes large subunit family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 110 kDa
Predicted: 131 kDa
Predicted: 131 kDa
NCBI Official Full Name
AP-3 complex subunit delta-1 isoform 2
NCBI Official Synonym Full Names
adaptor related protein complex 3 subunit delta 1
NCBI Official Symbol
AP3D1
NCBI Official Synonym Symbols
ADTD; HPS10; hBLVR
NCBI Protein Information
AP-3 complex subunit delta-1
UniProt Protein Name
AP-3 complex subunit delta-1
UniProt Gene Name
AP3D1
UniProt Entry Name
AP3D1_HUMAN
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Product Notes
The AP3D1 ap3d1 (Catalog #AAA328769) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AP3D1 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus and may cross-react with other species as described in the data sheet. AAA Biotech's AP3D1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the AP3D1 ap3d1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AP3D1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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