WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.)
Rabbit anti-Human, Mouse APLF Polyclonal Antibody | anti-APLF antibody
APLF Polyclonal Antibody
Gene Names
APLF; APFL; PALF; Xip1; C2orf13
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Synonyms
APLF, Antibody; APLF Polyclonal Antibody; APLF; C2orf13; PALF; XIP1; Aprataxin and PNK-like factor; Apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; XRCC1-interacting protein 1; anti-APLF antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Applicable Applications for anti-APLF antibody
IHC (Immunohistochemistry), WB (Western Blot)
Notes
ECO:0000303|PubMed:17353262, ECO:0000312|HGNC: HGNC:28724
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.)
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.)
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.)
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.)
Related Product Information for anti-APLF antibody
Nuclease involved in single-strand and double-strand DNA break repair (PubMed:17396150). Recruited to sites of DNA damage through interaction with poly (ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions (PubMed:17396150, PubMed:21211721). Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage (PubMed:17396150). Together with PARP3, promotes the retention of the LIG4-XRCC4 complex on chromatin and accelerate DNA ligation during non-homologous end-joining (NHEJ)(PubMed:21211721).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,956 Da
NCBI Official Full Name
aprataxin and PNK-like factor
NCBI Official Synonym Full Names
aprataxin and PNKP like factor
NCBI Official Symbol
APLF
NCBI Official Synonym Symbols
APFL; PALF; Xip1; C2orf13
NCBI Protein Information
aprataxin and PNK-like factor; XRCC1-interacting protein 1; PNK and APTX-like FHA protein; aprataxin- and PNK-like factor; apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein
UniProt Protein Name
Aprataxin and PNK-like factor
UniProt Gene Name
APLF
UniProt Synonym Gene Names
C2orf13; PALF; XIP1
UniProt Entry Name
APLF_HUMAN
Similar Products
Product Notes
The APLF aplf (Catalog #AAA294272) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APLF Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's APLF can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the APLF aplf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APLF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.