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product-image-AAA40599_IHC10.gif IHC (Immunohistochemistry) (Immunohistochemistry of APO E in mouse brain tissue with APO E Antibody at 5 μg/mL.)

Rabbit APO-E Polyclonal Antibody | anti-APOE antibody

APO-E Antibody

Gene Names
APOE; AD2; LPG; APO-E; LDLCQ5
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Purity
APO-E Antibody is affinity chromatography purified via peptide column.
Synonyms
APO-E, Antibody; APO-E Antibody; APO-E; AD2; LPG; LDLCQ5; Apolipoprotein E; Apo-E; apolipoprotein E; anti-APOE antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
APO-E Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid; APO-E Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration
1 mg/mL (varies by lot)
Applicable Applications for anti-APOE antibody
WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA
Homology
Predicted species reactivity based on immunogen sequence: Pig: (78%)
Immunogen
APO-E antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E.
The immunogen is located within amino acids 220 - 270 of APO-E.
Positive Control
1) MBS151732 - Human Brain Tissue Lysate
2) MBS154328 - Human Liver Tissue Slide
Preparation and Storage
Short Term: 4°C
Long Term: -20°C

IHC (Immunohistochemistry)

(Immunohistochemistry of APO E in mouse brain tissue with APO E Antibody at 5 μg/mL.)

product-image-AAA40599_IHC10.gif IHC (Immunohistochemistry) (Immunohistochemistry of APO E in mouse brain tissue with APO E Antibody at 5 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of APO E in mouse brain tissue with APO E Antibody at 20 μg/mL.Green: APO E antibody (7333)Red: Phylloidin stainingBlue: DAPI staining)

product-image-AAA40599_IF11.gif IF (Immunofluorescence) (Immunofluorescence of APO E in mouse brain tissue with APO E Antibody at 20 μg/mL.Green: APO E antibody (7333)Red: Phylloidin stainingBlue: DAPI staining)

IHC (Immunohiostchemistry)

(Immunohistochemistry of APO-E inhuman liver tissue with APO-E antibody at 2.5 μg/ml.)

product-image-AAA40599_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of APO-E inhuman liver tissue with APO-E antibody at 2.5 μg/ml.)

WB (Western Blot)

(Western blot analysis of APO-E in human brain tissue lysate with APO-E antibody at (A) 0.5 and (B) 1 μg/mL.)

product-image-AAA40599_WB15.gif WB (Western Blot) (Western blot analysis of APO-E in human brain tissue lysate with APO-E antibody at (A) 0.5 and (B) 1 μg/mL.)
Related Product Information for anti-APOE antibody
APO-E Antibody: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E (APO-E), a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in APO-E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
348
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 35 kDa
Observed: 34 kDa
NCBI Official Full Name
apolipoprotein E isoform b
NCBI Official Synonym Full Names
apolipoprotein E
NCBI Official Symbol
APOE
NCBI Official Synonym Symbols
AD2; LPG; APO-E; LDLCQ5
NCBI Protein Information
apolipoprotein E; apolipoprotein E3
UniProt Protein Name
Apolipoprotein E
UniProt Gene Name
APOE
UniProt Synonym Gene Names
Apo-E
UniProt Entry Name
APOE_HUMAN

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Product Notes

The APOE apoe (Catalog #AAA40599) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APO-E Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's APO-E can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA. Researchers should empirically determine the suitability of the APOE apoe for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APO-E, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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