WB (Western Blot)
(Anti-ASIC3 antibody, AAA45435, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Testis Tissue LysateLane 3: U87 Cell LysateLane 4: NEURO Cell LysateLane 5: SMMC Cell Lysate)
Rabbit ASIC3 Polyclonal Antibody | anti-ASIC3 antibody
Anti-ASIC3 antibody
Gene Names
ASIC3; ACCN3; TNaC1; DRASIC; SLNAC1
Reactivity
Human, Mouse, Rat
Applications
Flow Cytometry, Functional Assay, Western Blot
Purity
Immunogen affinity purified.
Synonyms
ASIC3, Antibody; Anti-ASIC3 antibody; Acid-sensing ion channel 3; acid-sensing(proton-gated) ion channel 3; ACCN 3 antibody; ACCN3 antibody; ACCN3_HUMAN antibody; Acid sensing ion channel 3 antibody; Acid-sensing ion channel 3 antibody; Amiloride sensitive cation channel 3 antibody; Amiloride sensitive cation channel 3 testis antibody; Amiloride-sensitive cation channel 3 antibody; ASIC 3 antibody; ASIC3 antibody; DRASIC antibody; hASIC 3 antibody; hASIC3 antibody; hTNaC 1 antibody; hTNaC1 antibody; Modulatory subunit of ASIC 2a antibody; Modulatory subunit of ASIC2a antibody; Neuronal amiloride sensitive cation channel 3 antibody; Neuronal amiloride-sensitive cation channel 3 antibody; Proton gated cation channel subunit antibody; SLNAC 1 antibody; SLNAC1 antibody; Testis sodium channel 1 antibody; TNaC 1 antibody; TNaC1 antibody; anti-ASIC3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross-reactivity with other proteins
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized ; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Sequence Length
531
Applicable Applications for anti-ASIC3 antibody
FCM/FACS (Flow Cytometry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human ASIC3, different from the related rat and mouse sequences by two amino acids.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Recommended Detection Systems
MBS recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (please inquire) for Western blot.
Preparation and Storage
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
WB (Western Blot)
(Anti-ASIC3 antibody, AAA45435, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Testis Tissue LysateLane 3: U87 Cell LysateLane 4: NEURO Cell LysateLane 5: SMMC Cell Lysate)
WB (Western Blot)
(Anti-ASIC3 antibody, AAA45435, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Testis Tissue LysateLane 3: U87 Cell LysateLane 4: NEURO Cell LysateLane 5: SMMC Cell Lysate)
Related Product Information for anti-ASIC3 antibody
Background: ASIC3(Acid-Sensing Ion Channel3), also known as TESTIS SODIUM CHANNEL 1(TNAC1) or DORSAL ROOT ACID-SENSING ION CHANNEL(DRASIC), is a protein that in humans is encoded by the ASIC3 gene. ASIC3 belongs to a family of acid-sensing channel proteins that are structurally related to epithelial sodium channel proteins and support acid-activated membrane currents. By radiation hybrid analysis, de Weille et al.(1998) mapped the ACCN3 gene to chromosome 7q35. De Weille et al.(1998) found that human ASIC3 supported an H(+)-gated cation current in COS cells with kinetics similar to those of rat Asic3. Babinski et al.(1999) expressed homomeric human ASIC3 channels in Xenopus oocytes and found that rapid reduction in extracellular pH resulted in a biphasic response characterized by a fast and rapidly desensitizing current followed by a slow and sustained current that returned to baseline only on return to physiologic pH.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Acid-sensing ion channel 3
NCBI Official Synonym Full Names
acid-sensing (proton-gated) ion channel 3
NCBI Official Symbol
ASIC3
NCBI Official Synonym Symbols
ACCN3; TNaC1; DRASIC; SLNAC1
NCBI Protein Information
acid-sensing ion channel 3; testis sodium channel 1; modulatory subunit of ASIC2a; proton-gated cation channel subunit; amiloride-sensitive cation channel 3, testis; neuronal amiloride-sensitive cation channel 3
UniProt Protein Name
Acid-sensing ion channel 3
UniProt Gene Name
ASIC3
UniProt Synonym Gene Names
ACCN3; SLNAC1; TNAC1; ASIC3; hASIC3; hTNaC1
UniProt Entry Name
ASIC3_HUMAN
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Product Notes
The ASIC3 asic3 (Catalog #AAA45435) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ASIC3 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ASIC3 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), WB (Western Blot). Researchers should empirically determine the suitability of the ASIC3 asic3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASIC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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