WB (Western Blot)
(Western blot analysis of ASPM using HeLa whole cell lysates)
Rabbit anti-Human ASPM Polyclonal Antibody | anti-ASPM antibody
ASPM Antibody
Gene Names
ASPM; ASP; MCPH5; Calmbp1
Reactivity
Human
Applications
ELISA, Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
ASPM, Antibody; ASPM Antibody; anti-ASPM antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
ASPM antibody detects endogenous levels of total ASPM
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1892
Applicable Applications for anti-ASPM antibody
ELISA, WB (Western Blot)
Immunogen
A synthesized peptide derived from human ASPM
Subcellular Location
Cytoskeleton; Nucleus
Predicted Cross Reactivity
Bovine, Horse, Sheep, Dog
Similarity
Bovine (82%), Horse (100%), Sheep (82%), Dog (90%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of ASPM using HeLa whole cell lysates)
WB (Western Blot)
(Western blot analysis of ASPM using HeLa whole cell lysates)
WB (Western Blot)
(Western blot analysis of extracts from various samples, using ASPM Antibody. Lane 1: 293 treated with blocking peptide. Lane 2: 293; Lane 3: Hela;)
WB (Western Blot)
(Western blot analysis of extracts from various samples, using ASPM Antibody. Lane 1: 293 treated with blocking peptide. Lane 2: 293; Lane 3: Hela;)
Related Product Information for anti-ASPM antibody
Function: Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex (PubMed:28436967). May have a preferential role in regulating neurogenesis.
Subunit Structure: Interacts with KATNA1 and KATNB1; katanin complex formation KATNA1:KATNB1 is required for the association.
Subunit Structure: Interacts with KATNA1 and KATNB1; katanin complex formation KATNA1:KATNB1 is required for the association.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 410 kDa
Predicted: 410 kDa
Predicted: 410 kDa
NCBI Official Full Name
abnormal spindle-like microcephaly-associated protein isoform 2
NCBI Official Synonym Full Names
abnormal spindle microtubule assembly
NCBI Official Symbol
ASPM
NCBI Official Synonym Symbols
ASP; MCPH5; Calmbp1
NCBI Protein Information
abnormal spindle-like microcephaly-associated protein
UniProt Protein Name
Abnormal spindle-like microcephaly-associated protein
UniProt Gene Name
ASPM
UniProt Synonym Gene Names
MCPH5; Asp homolog
Similar Products
Product Notes
The ASPM aspm (Catalog #AAA322716) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ASPM Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ASPM can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the ASPM aspm for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASPM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.