IF (Immunofluorescence)
(Immunofluorescence of ATG2B in K562 cells with ATG2B antibody at 20 μg/mL.)
Rabbit anti-Human ATG2B Polyclonal Antibody | anti-ATG2B antibody
ATG2B Antibody
Gene Names
ATG2B; C14orf103
Reactivity
Human
Applications
Immunofluorescence, Western Blot, ELISA
Purity
ATG2B Antibody is affinity chromatography purified via peptide column.
Synonyms
ATG2B, Antibody; ATG2B Antibody; ATG2B; C14orf103; Autophagy-related protein 2 homolog B; autophagy-related protein 2 homolog B; anti-ATG2B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
ATG2B antibody is predicted to not cross-react with other ATG2A.
Purity/Purification
ATG2B Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
2078
Applicable Applications for anti-ATG2B antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
ATG2B antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATG2B.
Buffer
ATG2B Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ATG2B antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of ATG2B in K562 cells with ATG2B antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of ATG2B in K562 cells with ATG2B antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of ATG2B in K562 cell lysate with ATG2B antibody at (A) 1 and (B) 2 μg/ml)
WB (Western Blot)
(Western blot analysis of ATG2B in K562 cell lysate with ATG2B antibody at (A) 1 and (B) 2 μg/ml)
Related Product Information for anti-ATG2B antibody
ATG2B Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is ATG2B, one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas, suggesting that deregulating the autophagy process may contribute to cancer development.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
229 kDa
NCBI Official Full Name
autophagy-related protein 2 homolog B
NCBI Official Synonym Full Names
autophagy related 2B
NCBI Official Symbol
ATG2B
NCBI Official Synonym Symbols
C14orf103
NCBI Protein Information
autophagy-related protein 2 homolog B; ATG2 autophagy related 2 homolog B
UniProt Protein Name
Autophagy-related protein 2 homolog B
UniProt Gene Name
ATG2B
UniProt Synonym Gene Names
C14orf103
UniProt Entry Name
ATG2B_HUMAN
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Product Notes
The ATG2B atg2b (Catalog #AAA40140) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATG2B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ATG2B can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ATG2B atg2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATG2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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