IHC (Immunohiostchemistry)
(Immunohistochemistry of ATG4A in human spleen tissue with ATG4A antibody at 5 μg/ml.)
Rabbit ATG4A Polyclonal Antibody | anti-ATG4A antibody
ATG4A Antibody
Gene Names
ATG4A; APG4A; AUTL2
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
ATG4A antibody is affinity chromatography purified via peptide column.
Synonyms
ATG4A, Antibody; ATG4A Antibody; Autophagy related 4A cysteine peptidase; APG4-A; AUTL2; autophagy related 4A, cysteine peptidase; anti-ATG4A antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ATG4A antibody is human, mouse and rat reactive. At least two isoforms of ATG4A are known to exist; this antibody will detect both isoforms. ATG4A is predicted to not cross-react with other ATG4 proteins.
Purity/Purification
ATG4A antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
398
Applicable Applications for anti-ATG4A antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
ATG4A antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ATG4A.
Buffer
ATG4A antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ATG4A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IHC (Immunohiostchemistry)
(Immunohistochemistry of ATG4A in human spleen tissue with ATG4A antibody at 5 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of ATG4A in human spleen tissue with ATG4A antibody at 5 μg/ml.)
WB (Western Blot)
(Western blot analysis of ATG4A in EL4 cell lysate with ATG4A antibody at (A) 1 and (B) 2 μg/ml.)
WB (Western Blot)
(Western blot analysis of ATG4A in EL4 cell lysate with ATG4A antibody at (A) 1 and (B) 2 μg/ml.)
Related Product Information for anti-ATG4A antibody
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). ATG4A, also known as AUTL2, is one of four mammalian orthologs of the yeast ATG4 protein; all four are cysteine proteases (3). ATG4 is required for ATG8 conjugation to phosphatidylethanolamine on autophagosomal membranes. In mammals, each ATG4 homolog shows a selective preference for the ATG8 homologs (4).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 48 kDa
Observed: 44 kDa
Observed: 44 kDa
NCBI Official Full Name
cysteine protease ATG4A isoform a
NCBI Official Synonym Full Names
autophagy related 4A, cysteine peptidase
NCBI Official Symbol
ATG4A
NCBI Official Synonym Symbols
APG4A; AUTL2
NCBI Protein Information
cysteine protease ATG4A; hAPG4A; autophagin 2; autophagin-2; APG4 autophagy 4 homolog A; AUT-like 2 cysteine endopeptidase; ATG4 autophagy related 4 homolog A; AUT-like 2, cysteine endopeptidase; autophagy-related protein 4 homolog A; autophagy-related cysteine endopeptidase 2
UniProt Protein Name
Cysteine protease ATG4A
UniProt Gene Name
ATG4A
UniProt Synonym Gene Names
APG4A; AUTL2; hAPG4A
UniProt Entry Name
ATG4A_HUMAN
Similar Products
Product Notes
The ATG4A atg4a (Catalog #AAA40648) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATG4A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ATG4A can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ATG4A atg4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATG4A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.