IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using ATG4B antibody.)
Rabbit anti-Human, Mouse ATG4B Polyclonal Antibody | anti-ATG4B antibody
ATG4B Antibody
Gene Names
ATG4B; APG4B; AUTL1
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
ATG4B, Antibody; ATG4B Antibody; Cysteine protease ATG4B; EC 3.4.22.-; Autophagy-related protein 4 homolog B; hAPG4B; Autophagin-1; anti-ATG4B antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total ATG4B protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
393
Applicable Applications for anti-ATG4B antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human ATG4B.
Target Name
ATG4B
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using ATG4B antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using ATG4B antibody.)
WB (Western Blot)
(Western blot analysis of extracts from Jurkat cells, using ATG4B antibody.)
WB (Western Blot)
(Western blot analysis of extracts from Jurkat cells, using ATG4B antibody.)
Related Product Information for anti-ATG4B antibody
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.Kabeya Y., J. Cell Sci. 117:2805-2812(2004).Marino G., J. Biol. Chem. 278:3671-3678(2003).Ota T.,Nat. Genet. 36:40-45(2004).
Product Categories/Family for anti-ATG4B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,622 Da
NCBI Official Full Name
cysteine protease ATG4B isoform a
NCBI Official Synonym Full Names
autophagy related 4B, cysteine peptidase
NCBI Official Symbol
ATG4B
NCBI Official Synonym Symbols
APG4B; AUTL1
NCBI Protein Information
cysteine protease ATG4B
UniProt Protein Name
Cysteine protease ATG4B
UniProt Gene Name
ATG4B
UniProt Synonym Gene Names
APG4B; AUTL1; KIAA0943; hAPG4B
UniProt Entry Name
ATG4B_HUMAN
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ATG4B Antibody
Host: Rabbit
Reactivity: Human, Mouse
Apps: Immunohistochemistry, Western Blot, ELISA
ATG4B Antibody
Host: Rabbit
Reactivity: Human, mouse
Apps: Immunohistochemistry, ELISA, Western Blot
Product Notes
The ATG4B atg4b (Catalog #AAA305269) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATG4B Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ATG4B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ATG4B atg4b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATG4B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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