IF (Immunofluorescence)
(Confocal immunofluorescent analysis of AVP Antibody (Center) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)
Rabbit anti-Human AVP Polyclonal Antibody | anti-AVP antibody
AVP Antibody (Center)
Gene Names
AVP; VP; ADH; ARVP; AVRP; AVP-NPII
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
AVP, Antibody; AVP Antibody (Center); Vasopressin-neurophysin 2-copeptin; AVP-NPII; Arg-vasopressin; Arginine-vasopressin; Neurophysin 2; Neurophysin-II; Copeptin; AVP; ARVP; VP; anti-AVP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
This AVP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-129 amino acids from the Central region of human AVP.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
102-129
Sequence Length
164
Applicable Applications for anti-AVP antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Function
Neurophysin 2 specifically binds vasopressin.
Cellular Location
Secreted.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of AVP Antibody (Center) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of AVP Antibody (Center) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)
IHC (Immunohiostchemistry)
(AVP Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AVP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(AVP Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AVP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Anti-AVP Antibody (Center) at 1:1000 dilution+ ZR-75-1 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-RabbitIgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 17 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(Anti-AVP Antibody (Center) at 1:1000 dilution+ ZR-75-1 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-RabbitIgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 17 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-AVP antibody
This gene encodes a precursor protein consisting of
arginine vasopressin and two associated proteins, neurophysin 2 and
a glycopeptide, copeptin. Arginine vasopressin is a posterior
pituitary hormone which is synthesized in the supraoptic nucleus
and paraventricular nucleus of the hypothalamus. Along with its
carrier protein, neurophysin 2, it is packaged into neurosecretory
vesicles and transported axonally to the nerve endings in the
neurohypophysis where it is either stored or secreted into the
bloodstream. The precursor is thought to be activated while it is
being transported along the axon to the posterior pituitary.
Arginine vasopressin acts as a growth factor by enhancing pH
regulation through acid-base transport systems. It has a direct
antidiuretic action on the kidney, and also causes vasoconstriction
of the peripheral vessels. This hormone can contract smooth muscle
during parturition and lactation. It is also involved in cognition,
tolerance, adaptation and complex sexual and maternal behaviour, as
well as in the regulation of water excretion and cardiovascular
functions.
arginine vasopressin and two associated proteins, neurophysin 2 and
a glycopeptide, copeptin. Arginine vasopressin is a posterior
pituitary hormone which is synthesized in the supraoptic nucleus
and paraventricular nucleus of the hypothalamus. Along with its
carrier protein, neurophysin 2, it is packaged into neurosecretory
vesicles and transported axonally to the nerve endings in the
neurohypophysis where it is either stored or secreted into the
bloodstream. The precursor is thought to be activated while it is
being transported along the axon to the posterior pituitary.
Arginine vasopressin acts as a growth factor by enhancing pH
regulation through acid-base transport systems. It has a direct
antidiuretic action on the kidney, and also causes vasoconstriction
of the peripheral vessels. This hormone can contract smooth muscle
during parturition and lactation. It is also involved in cognition,
tolerance, adaptation and complex sexual and maternal behaviour, as
well as in the regulation of water excretion and cardiovascular
functions.
Product Categories/Family for anti-AVP antibody
References
Abu Libdeh, A., et al. Eur. J. Endocrinol. 162(2):221-226(2010)
Cirillo, M. Kidney Int. 77(1):5-6(2010)
Meijer, E., et al. Kidney Int. 77(1):29-36(2010)
Birk, J., et al. J. Cell. Sci. 122 (PT 21), 3994-4002 (2009)
Cirillo, M. Kidney Int. 77(1):5-6(2010)
Meijer, E., et al. Kidney Int. 77(1):29-36(2010)
Birk, J., et al. J. Cell. Sci. 122 (PT 21), 3994-4002 (2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
vasopressin-neurophysin 2-copeptin preproprotein
NCBI Official Synonym Full Names
arginine vasopressin
NCBI Official Symbol
AVP
NCBI Official Synonym Symbols
VP; ADH; ARVP; AVRP; AVP-NPII
NCBI Protein Information
vasopressin-neurophysin 2-copeptin
UniProt Protein Name
Vasopressin-neurophysin 2-copeptin
UniProt Gene Name
AVP
UniProt Synonym Gene Names
ARVP; VP
UniProt Entry Name
NEU2_HUMAN
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Product Notes
The AVP avp (Catalog #AAA285660) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 102-129. The AVP Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AVP can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the AVP avp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AVP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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