IF (Immunofluorescence)
(Immunofluorescence of B2M in mouse brain tissue with B2M antibody at 20 μg/mL.)
Rabbit anti-Human B2M Polyclonal Antibody | anti-B2M antibody
B2M Antibody
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
B2M Antibody is affinity chromatography purified via peptide column.
Synonyms
B2M, Antibody; B2M Antibody; B2M; Beta-2-microglobulin; beta-2-microglobulin; anti-B2M antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
B2M antibody is human reactive.
Purity/Purification
B2M Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
119
Applicable Applications for anti-B2M antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
B2M antibody was raised against a 15 amino acid peptide near the carboxy terminus of human B2M.
Buffer
B2M Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
B2M antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of B2M in mouse brain tissue with B2M antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of B2M in mouse brain tissue with B2M antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of B2M in mouse brain tissue with B2M antibody 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of B2M in mouse brain tissue with B2M antibody 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of B2M in SK-N-SH cell lysate with B2M antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of B2M in SK-N-SH cell lysate with B2M antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-B2M antibody
B2M Antibody: Beta2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system (1,2). B2M is involved in the presentation of peptide antigens to the immune system and plays a critically important role in immune system function (3). It is expressed on nearly all nucleated cells and contains one Ig-like C1-type (immunoglobulin-like) domain (2,3). Mutations in the Beta 2-microglobulin gene can enhance the progression of malignant melanoma and osteoarthropathy (4,5).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 13 kDa
Observed: 12 kDa
Observed: 12 kDa
NCBI Official Full Name
beta-2-microglobulin
NCBI Official Synonym Full Names
beta-2-microglobulin
NCBI Official Symbol
B2M
NCBI Protein Information
beta-2-microglobulin; beta-2-microglobin; beta chain of MHC class I molecules
UniProt Protein Name
Beta-2-microglobulin
UniProt Gene Name
B2M
UniProt Entry Name
B2MG_HUMAN
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Product Notes
The B2M b2m (Catalog #AAA40651) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The B2M Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's B2M can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the B2M b2m for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "B2M, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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