IHC (Immunohistochemisry)
(Anti-BACE1 antibody IHC of human brain, Alzheimer's. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit BACE1 / BACE Polyclonal Antibody | anti-BACE1 antibody
Rabbit Polyclonal to Human BACE1 / BACE
Gene Names
BACE1; ASP2; BACE; HSPC104
Reactivity
Gibbon, Gorilla, Human, Monkey, RatPredicted Reactivity: Mouse, Bovine, Hamster (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
BACE1 / BACE, Antibody; Rabbit Polyclonal to Human BACE1 / BACE; Anti-BACE1 / BACE Antibody (N-Terminus) IHC-plus; BACE1; APP beta-secretase; Asp 2; ASP2; Aspartyl protease 2; Aspartylprotease 2; Beta-secretase; Beta-site APP-cleaving enzyme; BACE; HSPC104; KIAA1149; B-Secretase; Beta-secretase 1; Memapsin-2; Human BACE1; anti-BACE1 antibody
Host
Rabbit
Reactivity
Gibbon, Gorilla, Human, Monkey, Rat
Predicted Reactivity: Mouse, Bovine, Hamster (at least 90% immunogen sequence identity)
Predicted Reactivity: Mouse, Bovine, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human BACE1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ZBTB47 (44%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
501
Applicable Applications for anti-BACE1 antibody
IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from near N-terminus of human BACE1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Rat (100%); Mouse, Bovine, Hamster, Panda (94%); Bat (89%).
Immunogen Type
Synthetic peptide
Immunogen
BACE1 / BACE antibody was raised against synthetic 18 amino acid peptide from near N-terminus of human BACE1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Rat (100%); Mouse, Bovine, Hamster, Panda (94%); Bat (89%); Elephant, Horse, Rabbit (83%).
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
IHC (Immunohistochemisry)
(Anti-BACE1 antibody IHC of human brain, Alzheimer's. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemisry)
(Anti-BACE1 antibody IHC of human brain, Alzheimer's. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohiostchemistry)
(Anti-BACE1 / BACE antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohiostchemistry)
(Anti-BACE1 / BACE antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-BACE1 / BACE antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-BACE1 / BACE antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-BACE1 antibody
Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Product Categories/Family for anti-BACE1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,107 Da
NCBI Official Full Name
beta-secretase 1 isoform A preproprotein
NCBI Official Synonym Full Names
beta-site APP-cleaving enzyme 1
NCBI Official Symbol
BACE1
NCBI Official Synonym Symbols
ASP2; BACE; HSPC104
NCBI Protein Information
beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme
UniProt Protein Name
Beta-secretase 1
UniProt Gene Name
BACE1
UniProt Synonym Gene Names
BACE; KIAA1149; ASP2; Asp 2; Beta-site APP cleaving enzyme 1
UniProt Entry Name
BACE1_HUMAN
Similar Products
Product Notes
The BACE1 bace1 (Catalog #AAA50675) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human BACE1 / BACE reacts with Gibbon, Gorilla, Human, Monkey, Rat Predicted Reactivity: Mouse, Bovine, Hamster (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's BACE1 / BACE can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the BACE1 bace1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BACE1 / BACE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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