WB (Western Blot)
Rabbit BACE2 B Polyclonal Antibody | anti-BACE2 B antibody
BACE2 B Antibody
Gene Names
BACE2; ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1
Reactivity
Human, Monkey
Applications
Western Blot, Immunoprecipitation, ELISA
Synonyms
BACE2 B, Antibody; BACE2 B Antibody; ALP 56; ASP1; ASP21; Aspartic Like Protease 56kDa; Downs Syndrome Region Aspartic Protease; DRAP; Memapsin-1; Membrane associated aspartic protease 1; Theta-secretase antibody; anti-BACE2 B antibody
Host
Rabbit
Reactivity
Human, Monkey
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.55-0.59 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
396
Applicable Applications for anti-BACE2 B antibody
WB (Western Blot), IP (Immunoprecipitation), ELISA
Immunogen
Synthetic peptide taken within amino acid region 350-396 on human BACE2B protein.
Expression
Neurons within the hippocampus, frontal cortex and temporal cortex. Lower expression in most peripheral tissues and at higher levels in colon, kidney, pancreas, placenta, prostate, stomach and trachea. Also found in spinal cord, medulla oblongata, substania nigra and locus coruleus. Expressed in ductal epithelium of prostate.
Molecular Function
Aspartic-type endopeptidase activity.
Structure
Belongs to the peptidase A1 family.
Subcellular Location
Endoplasmic Reticulum, Endosome, Golgi apparatus; Membrane
Preparation and Storage
-20 degree C for long term storage
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-BACE2 B antibody
Affinity Purified beta-secretase 2 isoform B preproprotein Antibody
Responsible for the proteolytic processing of the amyloid precursor protein. Cleaves APP between 690 and 691 leading to the generation and extracellular release of beta-cleaved soluble APP and C-terminal fragment which is later released by gamma-secretase.
Responsible for the proteolytic processing of the amyloid precursor protein. Cleaves APP between 690 and 691 leading to the generation and extracellular release of beta-cleaved soluble APP and C-terminal fragment which is later released by gamma-secretase.
Product Categories/Family for anti-BACE2 B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,476 Da
NCBI Official Full Name
beta-secretase 2 isoform B preproprotein
NCBI Official Synonym Full Names
beta-site APP-cleaving enzyme 2
NCBI Official Symbol
BACE2
NCBI Official Synonym Symbols
ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1
NCBI Protein Information
beta-secretase 2
UniProt Protein Name
Beta-secretase 2
UniProt Gene Name
BACE2
UniProt Synonym Gene Names
AEPLC; ALP56; ASP21; ASP1; Asp 1; Beta-site APP cleaving enzyme 2; DRAP
UniProt Entry Name
BACE2_HUMAN
Similar Products
Product Notes
The BACE2 B bace2 (Catalog #AAA75676) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BACE2 B Antibody reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's BACE2 B can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), ELISA. Researchers should empirically determine the suitability of the BACE2 B bace2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BACE2 B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.