IF (Immunofluorescence)
(Immunofluorescence of BCAS3 in human breast carcinoma tissue with BCAS3 antibody at 20 μg/mL.)
Rabbit BCAS3 Polyclonal Antibody | anti-BCAS3 antibody
BCAS3 Antibody
Gene Names
BCAS3; MAAB; GAOB1
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
BCAS3 Antibody is affinity chromatography purified via peptide column.
Synonyms
BCAS3, Antibody; BCAS3 Antibody; BCAS3; MAAB; GAOB1; Breast carcinoma-amplified sequence 3; breast carcinoma amplified sequence 3; anti-BCAS3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
BCAS3 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
950
Applicable Applications for anti-BCAS3 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
BCAS3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human BCAS3.
Buffer
BCAS3 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
BCAS3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of BCAS3 in human breast carcinoma tissue with BCAS3 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of BCAS3 in human breast carcinoma tissue with BCAS3 antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of BCAS3 in human breast carcinoma with BCAS3 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of BCAS3 in human breast carcinoma with BCAS3 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of BCAS3 in rat brain tissue lysate with BCAS3 antibody at (A) 0.5 and (B) 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of BCAS3 in rat brain tissue lysate with BCAS3 antibody at (A) 0.5 and (B) 1 μg/mL.)
Related Product Information for anti-BCAS3 antibody
BCAS3 Antibody: The Breast carcinoma amplified sequence (BCAS3) gene is localized to 17q23, a region that is often amplified in breast cancers. Copy number gains at this region have also been reported in other tumors such as brain, lung, liver, testis and bladder. BCAS3 is thought to be an estrogen receptor (ER)-alpha co-activator that acts through PELP1, another ER-alpha that in turn activates BCAS3 expression. This may set up a positive feedback loop leading to ER-a signal amplification in the cell which may play a significant role in breast cancer. BCAS3 expression has also been observed in embryonic stem cells and vascular precursors, suggesting that it may also play a role in embryogenesis and tumor angiogenesis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
74,240 Da
NCBI Official Full Name
breast carcinoma amplified sequence 3, isoform CRA_f
NCBI Official Synonym Full Names
breast carcinoma amplified sequence 3
NCBI Official Symbol
BCAS3
NCBI Official Synonym Symbols
MAAB; GAOB1
NCBI Protein Information
breast carcinoma-amplified sequence 3; protein Maab1; BCAS4/BCAS3 fusion; metastasis associated antigen of breast cancer; breast carcinoma amplified sequence 4/3 fusion protein
UniProt Protein Name
Breast carcinoma-amplified sequence 3
UniProt Gene Name
BCAS3
UniProt Entry Name
BCAS3_HUMAN
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Product Notes
The BCAS3 bcas3 (Catalog #AAA39722) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCAS3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BCAS3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the BCAS3 bcas3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCAS3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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