IHC (Immunohiostchemistry)
(Immunohistochemistry of Bcl-rambo in human heart tissue with Bcl-rambo antibody at 10 ug/mL.)
Rabbit Bcl-rambo Polyclonal Antibody | anti-BCL2L13 antibody
Bcl-rambo Antibody
Gene Names
BCL2L13; MIL1; BCL-RAMBO; Bcl2-L-13
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Bcl-rambo, Antibody; Bcl-rambo Antibody; Bcl-2 like protein 13, Mil1; anti-BCL2L13 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
485
Applicable Applications for anti-BCL2L13 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 15 amino acid peptide from near the center of human Bcl-rambo.
Target Name
Bcl-rambo
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of Bcl-rambo in human heart tissue with Bcl-rambo antibody at 10 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of Bcl-rambo in human heart tissue with Bcl-rambo antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of Bcl-rambo in K562 cell lysate with Bcl-rambo antibody at (A) 2 and (B) 4 ug/mL.)
WB (Western Blot)
(Western blot analysis of Bcl-rambo in K562 cell lysate with Bcl-rambo antibody at (A) 2 and (B) 4 ug/mL.)
Related Product Information for anti-BCL2L13 antibody
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A novel, widely expressed member termed Bcl-rambo was recently identified. This protein is localized to mitochondria in mammalian cells and its overexpression induces apoptosis which could be blocked by co-expression of inhibitor of apoptosis proteins (IAPs) such as XIAP, cIAP1, and cIAP2. Bcl-rambo shows overall homology to the anti-apoptotic members containing BH motifs, but unlike Bcl-2, the C-terminal membrane anchor of Bcl-rambo is preceded by a unique 250 amino acid insertion. This region by itself can induce apoptosis more efficiently than the Bcl-2 homology regions, suggesting that Bcl-rambo may be important other pro-apoptotic pathways.
Product Categories/Family for anti-BCL2L13 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
34,601 Da
NCBI Official Full Name
BCL2-like 13 (apoptosis facilitator)
NCBI Official Synonym Full Names
BCL2-like 13 (apoptosis facilitator)
NCBI Official Symbol
BCL2L13
NCBI Official Synonym Symbols
MIL1; BCL-RAMBO; Bcl2-L-13
NCBI Protein Information
bcl-2-like protein 13
UniProt Protein Name
Bcl-2-like protein 13
UniProt Gene Name
BCL2L13
UniProt Synonym Gene Names
MIL1; Bcl2-L-13
UniProt Entry Name
B2L13_HUMAN
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Product Notes
The BCL2L13 bcl2l13 (Catalog #AAA304850) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bcl-rambo Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Bcl-rambo can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the BCL2L13 bcl2l13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bcl-rambo, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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