Rabbit anti-Human BCMA Polyclonal Antibody | anti-TNFRSF17 antibody

BCMA Antibody

Cat. Num. AAA40024

• Gene Names: TNFRSF17; BCM; BCMA; CD269; TNFRSF13A
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
• Purity: BCMA Antibody is affinity chromatography purified via peptide column.
• Synonyms: BCMA, Antibody; BCMA Antibody; BCMA; BCM; CD269; TNFRSF13A; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; tumor necrosis factor receptor superfamily, member 17; anti-TNFRSF17 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: BCMA Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid; Supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 184

• Applicable Applications for anti-TNFRSF17 antibody: WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA
• Conjugate: Unconjugated
• Immunogen: BCMA antibody was raised against a synthetic peptide mapping at the carboxy terminus of human BCMA.; The immunogen is located within the last 50 amino acids of BCMA.
• Positive Control: 1) Cat. No. MBS151739 - K562 Cell Lysate; 2) Cat. No. MBS151695 - U937 Cell Lysate; 3) Cat. No. MBS151674 - Human Spleen Tissue Lysate; 4) Cat. No. MBS154333 - Human Spleen Tissue Slide
• Preparation and Storage: Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of BCMA in Human Spleen tissue with BCMA antibody at 10 μg/mL.)

IHC (Immunohistochemisry)

(Immunohistochemistry of BCMA in human spleen tissue with BCMA antibody at 10 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of BCMA in human spleen tissue with BCMA antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of BCMA in (A) human spleen tissue lysate, (B) K562, and (C) U937 cell lysates with BCMA antibody at 5 μg/mL.)

Related Product Information for anti-TNFRSF17 antibody

BCMA Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-κB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.

NCBI and Uniprot Product Information

• NCBI GI #: 23238192
• NCBI GeneID: 608
• NCBI Accession #: NP_001183
• NCBI GenBank Nucleotide #: NM_001192.2
• UniProt Accession #: Q02223; Q2TQ40
• Molecular Weight: Predicted: 20 kDa; Observed: 27 kDa
• NCBI Official Full Name: tumor necrosis factor receptor superfamily member 17
• NCBI Official Synonym Full Names: tumor necrosis factor receptor superfamily, member 17
• NCBI Official Symbol: TNFRSF17
• NCBI Official Synonym Symbols: BCM; BCMA; CD269; TNFRSF13A
• NCBI Protein Information: tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein
• UniProt Protein Name: Tumor necrosis factor receptor superfamily member 17
• UniProt Gene Name: TNFRSF17
• UniProt Synonym Gene Names: BCM; BCMA
• UniProt Entry Name: TNR17_HUMAN