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Application Data
(Anti-Beclin 1 Picoband antibody, AAA45721-5.jpgAll lanes: Anti-Beclin-1 (AAA45721) at 0.5ug/mlLane 1: Colo320 Whole Cell Lysate at 40ugLane 2: HepG2 Whole Cell Lysate at 40ugLane 3: PANC Whole Cell Lysate at 40ugLane 4: A431 Whole Cell Lysate at 40ugLane 5: Smmc Whole Cell Lysate at 40ugLane 6: Jurkat Whole Cell Lysate at 40ugLane 7: SW620 Whole Cell Lysate at 40ugLane 8: U87 Whole Cell Lysate at 40ugPredicted bind size: 52KDObserved bind size: 60KD)
Rabbit Beclin 1 Polyclonal Antibody | anti-BECN1 antibody
Anti-Beclin 1 Antibody
Gene Names
BECN1; ATG6; VPS30; beclin1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Beclin 1, Antibody; Anti-Beclin 1 Antibody; Beclin-1; beclin 1, autophagy related; APG6 antibody; ATG 6 antibody; ATG6 antibody; ATG6 autophagy related 6 homolog antibody; Bcl-2-interacting protein beclin antibody; Beclin 1 (coiled coil moesin like BCL2 interacting protein) antibody; Beclin 1 autophagy related antibody; Beclin-1 antibody; Beclin1 antibody; BECN 1 antibody; BECN1 antibody; BECN1_HUMAN antibody; Coiled coil myosin like BCL2 interacting protein antibody; Coiled-coil myosin-like BCL2-interacting protein antibody; GT197 antibody; Protein GT197 antibody; VPS 30 antibody; VPS30 antibody; anti-BECN1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
450
Applicable Applications for anti-BECN1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
E Coli-derived human Beclin 1 recombinant protein (Position: M1-S354). Human Beclin 1 shares 97% amino acid (aa) sequence identity with both mouse and rat Beclin 1.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Application Data
(Anti-Beclin 1 Picoband antibody, AAA45721-5.jpgAll lanes: Anti-Beclin-1 (AAA45721) at 0.5ug/mlLane 1: Colo320 Whole Cell Lysate at 40ugLane 2: HepG2 Whole Cell Lysate at 40ugLane 3: PANC Whole Cell Lysate at 40ugLane 4: A431 Whole Cell Lysate at 40ugLane 5: Smmc Whole Cell Lysate at 40ugLane 6: Jurkat Whole Cell Lysate at 40ugLane 7: SW620 Whole Cell Lysate at 40ugLane 8: U87 Whole Cell Lysate at 40ugPredicted bind size: 52KDObserved bind size: 60KD)
Application Data
(Anti-Beclin 1 Picoband antibody, AAA45721-5.jpgAll lanes: Anti-Beclin-1 (AAA45721) at 0.5ug/mlLane 1: Colo320 Whole Cell Lysate at 40ugLane 2: HepG2 Whole Cell Lysate at 40ugLane 3: PANC Whole Cell Lysate at 40ugLane 4: A431 Whole Cell Lysate at 40ugLane 5: Smmc Whole Cell Lysate at 40ugLane 6: Jurkat Whole Cell Lysate at 40ugLane 7: SW620 Whole Cell Lysate at 40ugLane 8: U87 Whole Cell Lysate at 40ugPredicted bind size: 52KDObserved bind size: 60KD)
IHC (Immunohistochemistry)
(Anti-Beclin 1 Picoband antibody, AAA45721-4.JPGIHC(P): Rat Spleen Tissue)
IHC (Immunohistochemistry)
(Anti-Beclin 1 Picoband antibody, AAA45721-4.JPGIHC(P): Rat Spleen Tissue)
IHC (Immunohistochemisry)
(Anti-Beclin 1 Picoband antibody, AAA45721-3.JPGIHC(P): Rat Intestine Tissue)
IHC (Immunohistochemisry)
(Anti-Beclin 1 Picoband antibody, AAA45721-3.JPGIHC(P): Rat Intestine Tissue)
IHC (Immunohiostchemistry)
(Anti-Beclin 1 Picoband antibody, AAA45721-2.JPGIHC(P): Mouse Spleen Tissue)
IHC (Immunohiostchemistry)
(Anti-Beclin 1 Picoband antibody, AAA45721-2.JPGIHC(P): Mouse Spleen Tissue)
IHC (Immunohistochemistry)
(Anti-Beclin 1 Picoband antibody, AAA45721-1.JPGIHC(P): Mouse Intestine Tissue)
IHC (Immunohistochemistry)
(Anti-Beclin 1 Picoband antibody, AAA45721-1.JPGIHC(P): Mouse Intestine Tissue)
Related Product Information for anti-BECN1 antibody
Description: Rabbit IgG polyclonal antibody for Beclin-1(BECN1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: Beclin-1, also known as also known as ATG6 or VPS30 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy. This gene participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. Schizophrenia is associated with low levels of Beclin-1 in the hippocampus of the affected which causes diminished autophagywhich in turn results in increased neuronal cell death. It has been found that beclin-1 can promote autophagy in autophagy-defective yeast with a targeted disruption of apg6/vps30, and in human MCF7 breast carcinoma cells.
Background: Beclin-1, also known as also known as ATG6 or VPS30 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy. This gene participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. Schizophrenia is associated with low levels of Beclin-1 in the hippocampus of the affected which causes diminished autophagywhich in turn results in increased neuronal cell death. It has been found that beclin-1 can promote autophagy in autophagy-defective yeast with a targeted disruption of apg6/vps30, and in human MCF7 breast carcinoma cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
51,896 Da
NCBI Official Full Name
Beclin-1
NCBI Official Synonym Full Names
beclin 1, autophagy related
NCBI Official Symbol
BECN1
NCBI Official Synonym Symbols
ATG6; VPS30; beclin1
NCBI Protein Information
beclin-1; ATG6 autophagy related 6 homolog; coiled-coil myosin-like BCL2-interacting protein; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); beclin 1 (coiled-coil, moesin-like BCL2-interacting protein)
UniProt Protein Name
Beclin-1
UniProt Gene Name
BECN1
UniProt Synonym Gene Names
GT197
UniProt Entry Name
BECN1_HUMAN
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Product Notes
The BECN1 becn1 (Catalog #AAA45721) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Beclin 1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Beclin 1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the BECN1 becn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Beclin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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