WB (Western Blot)
(Western blot analysis of BEND3 in Evsa-T cells lysates using BEND3 antibody.)
Rabbit anti-Human, Mouse BEND3 Polyclonal Antibody | anti-BEND3 antibody
BEND3 Polyclonal Antibody
Gene Names
BEND3; KIAA1553
Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
BEND3, Antibody; BEND3 Polyclonal Antibody; anti-BEND3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody detects endogenous levels of BEND3 at Human, Mouse
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
828
Applicable Applications for anti-BEND3 antibody
WB (Western Blot)
Immunogen
Synthesized peptide derived from human BEND3
Function
Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination . Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites (By similarity). Stimulates the ERCC6L translocase and ATPase activities.
Subcellular Location
Nucleus . Nucleus, nucleolus . In the nucleus, observed in heterochromatic foci containing CBX1, CBX3, CBX5 and histone H3 trimethylated at 'Lys-9'. Released from chromatin during decondensation. Association with heterochromatin does not depend on sumoylation.
Expression
Expressed at least in heart, kidney, liver, ovary and spleen, with highest levels in spleen and lowest in heart. Expressed on the surface of T-cells.
Preparation and Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
WB (Western Blot)
(Western blot analysis of BEND3 in Evsa-T cells lysates using BEND3 antibody.)
WB (Western Blot)
(Western blot analysis of BEND3 in Evsa-T cells lysates using BEND3 antibody.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
91 kD
NCBI Official Full Name
BEN domain-containing protein 3
NCBI Official Synonym Full Names
BEN domain containing 3
NCBI Official Symbol
BEND3
NCBI Official Synonym Symbols
KIAA1553
NCBI Protein Information
BEN domain-containing protein 3
UniProt Protein Name
BEN domain-containing protein 3
UniProt Gene Name
BEND3
UniProt Synonym Gene Names
KIAA1553
UniProt Entry Name
BEND3_HUMAN
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Product Notes
The BEND3 bend3 (Catalog #AAA268853) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BEND3 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's BEND3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the BEND3 bend3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BEND3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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