IHC (Immunohistochemisry)
(Anti- HEXB antibody, AAA46076,IHC(P)IHC(P): Human Lung Cancer Tissue)
Rabbit Beta-hexosaminidase subunit beta Polyclonal Antibody | anti-HEXB antibody
Anti-HEXB Antibody
Gene Names
HEXB; ENC-1AS; HEL-248
Reactivity
Human. No cross reactivity with other proteins.
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Beta-hexosaminidase subunit beta, Antibody; Anti-HEXB Antibody; Beta hexosaminidase beta chain antibody; Beta hexosaminidase subunit beta antibody; Beta N acetylhexosaminidase antibody; Beta-hexosaminidase subunit beta chain A antibody; Beta-N-acetylhexosaminidase subunit beta antibody; Cervical cancer proto oncogene 7 protein antibody; Cervical cancer proto-oncogene 7 protein antibody; ENC 1AS antibody; HCC 7 antibody; HCC-7 antibody; HCC7 antibody; HEX B antibody; Hexb antibody; HEXB_HUMAN antibody; Hexosaminidase B (beta polypeptide) antibody; Hexosaminidase B antibody; Hexosaminidase subunit B antibody; HexosaminidaseB antibody; N acetyl beta glucosaminidase antibody; N-acetyl-beta-glucosaminidase subunit beta antibody; hexosaminidase B (beta polypeptide); anti-HEXB antibody
Host
Rabbit
Reactivity
Human. No cross reactivity with other proteins.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
556
Applicable Applications for anti-HEXB antibody
IHC (Immunohistochemistry), WB (Western Blot)
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
E.coli-derived human HEXB recombinant protein (Position: K381-M556). Human HEXB shares 75% and 73% amino acid (aa) sequences identity with mouse and rat HEXB, respectively.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemisry)
(Anti- HEXB antibody, AAA46076,IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohistochemisry)
(Anti- HEXB antibody, AAA46076,IHC(P)IHC(P): Human Lung Cancer Tissue)
WB (Western Blot)
(Anti- HEXB antibody, AAA46076, Western blottingAll lanes: Anti HEXB (AAA46076) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: HEPG2 Whole Cell Lysate at 40ugPredicted bind size: 63KDObserved bind size: 63KD)
WB (Western Blot)
(Anti- HEXB antibody, AAA46076, Western blottingAll lanes: Anti HEXB (AAA46076) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: HEPG2 Whole Cell Lysate at 40ugPredicted bind size: 63KDObserved bind size: 63KD)
WB (Western Blot)
(Anti- HEXB antibody, AAA46076, Western blottingAll lanes: Anti HEXB (AAA46076) at 0.5ug/mlWB: Recombinant Human HEXB Protein 0.5ngPredicted bind size: 38KDObserved bind size: 38KD)
WB (Western Blot)
(Anti- HEXB antibody, AAA46076, Western blottingAll lanes: Anti HEXB (AAA46076) at 0.5ug/mlWB: Recombinant Human HEXB Protein 0.5ngPredicted bind size: 38KDObserved bind size: 38KD)
Related Product Information for anti-HEXB antibody
Description: Rabbit IgG polyclonal antibody for Beta-hexosaminidase subunit beta(HEXB) detection. Tested with WB, IHC-P in Human.
Background: Beta-hexosaminidase subunit beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene. It is mapped to 5q13.3. HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity.
Background: Beta-hexosaminidase subunit beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene. It is mapped to 5q13.3. HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
63,111 Da
NCBI Official Full Name
beta-hexosaminidase subunit beta isoform 1 preproprotein
NCBI Official Synonym Full Names
hexosaminidase B (beta polypeptide)
NCBI Official Symbol
HEXB
NCBI Official Synonym Symbols
ENC-1AS; HEL-248
NCBI Protein Information
beta-hexosaminidase subunit beta; HCC-7; hexosaminidase subunit B; epididymis luminal protein 248; beta-N-acetylhexosaminidase subunit beta; cervical cancer proto-oncogene 7 protein; N-acetyl-beta-glucosaminidase subunit beta
UniProt Protein Name
Beta-hexosaminidase subunit beta
UniProt Gene Name
HEXB
UniProt Synonym Gene Names
Hexosaminidase subunit B; HCC-7
UniProt Entry Name
HEXB_HUMAN
Similar Products
Product Notes
The HEXB hexb (Catalog #AAA46076) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HEXB Antibody reacts with Human. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Beta-hexosaminidase subunit beta can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the HEXB hexb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Beta-hexosaminidase subunit beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.