ICC (Immunocytochemistry)
(Immunocytochemistry of BICD1 in Daudi cells with BICD1 antibody at 2.5 ug/mL.)
Rabbit BICD1 Polyclonal Antibody | anti-BICD1 antibody
BICD1 Antibody
Gene Names
BICD1; BICD
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
BICD1, Antibody; BICD1 Antibody; Bicaudal D homolog 1; anti-BICD1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
At least two isoforms of BICD1 are known to exist; this antibody will only recognize the larger isoform.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
975
Applicable Applications for anti-BICD1 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 15 amino acid peptide from near the carboxy terminus of human BICD1.
Target Name
BICD1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of BICD1 in Daudi cells with BICD1 antibody at 2.5 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of BICD1 in Daudi cells with BICD1 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of BICD1 in Daudi cell lysate with BICD1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of BICD1 in Daudi cell lysate with BICD1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-BICD1 antibody
BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells.
Product Categories/Family for anti-BICD1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
95,739 Da
NCBI Official Full Name
protein bicaudal D homolog 1 isoform 1
NCBI Official Synonym Full Names
bicaudal D homolog 1 (Drosophila)
NCBI Official Symbol
BICD1
NCBI Official Synonym Symbols
BICD
NCBI Protein Information
protein bicaudal D homolog 1
UniProt Protein Name
Protein bicaudal D homolog 1
UniProt Gene Name
BICD1
UniProt Synonym Gene Names
Bic-D 1
UniProt Entry Name
BICD1_HUMAN
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Product Notes
The BICD1 bicd1 (Catalog #AAA305972) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BICD1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BICD1 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the BICD1 bicd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BICD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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