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product-image-AAA288618_IHC13.jpg IHC (Immunohiostchemistry) (BIRC2 Antibody (Center) (AAA288618)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BIRC2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Rabbit BIRC2 Polyclonal Antibody | anti-BIRC2 antibody

BIRC2 Antibody (Center)

Gene Names
BIRC2; API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
BIRC2, Antibody; BIRC2 Antibody (Center); Baculoviral IAP repeat-containing protein 2; 632-; C-IAP1; IAP homolog B; Inhibitor of apoptosis protein 2; IAP-2; hIAP-2; hIAP2; RING finger protein 48; TNFR2-TRAF-signaling complex protein 2; BIRC2; API1; IAP2; MIHB; RNF48; anti-BIRC2 antibody
Ordering
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This BIRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-244 amino acids from the Central region of human BIRC2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.33 (varies by lot)
Sequence Positions
216-244
Sequence Length
618
Applicable Applications for anti-BIRC2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohiostchemistry)

(BIRC2 Antibody (Center) (AAA288618)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BIRC2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

product-image-AAA288618_IHC13.jpg IHC (Immunohiostchemistry) (BIRC2 Antibody (Center) (AAA288618)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BIRC2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(BIRC2 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the BIRC2 antibody detected the BIRC2 protein (arrow).)

product-image-AAA288618_WB15.jpg WB (Western Blot) (BIRC2 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the BIRC2 antibody detected the BIRC2 protein (arrow).)
Related Product Information for anti-BIRC2 antibody
The protein encoded by this gene is a member of a family
of proteins that inhibits apoptosis by binding to tumor necrosis
factor receptor-associated factors TRAF1 and TRAF2, probably by
interfering with activation of ICE-like proteases. This encoded
protein inhibits apoptosis induced by serum deprivation and
menadione, a potent inducer of free radicals.
Product Categories/Family for anti-BIRC2 antibody
References
Hinz, M., et al. Mol. Cell 40(1):63-74(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Meng, N., et al. J. Cell. Physiol. 225(1):174-179(2010)
Burke, S.P., et al. J. Biol. Chem. 285(39):30061-30068(2010)
Mace, P.D., et al. J. Mol. Biol. 400(1):8-15(2010)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
329
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
69900
NCBI Official Full Name
baculoviral IAP repeat-containing protein 2 isoform 1
NCBI Official Synonym Full Names
baculoviral IAP repeat containing 2
NCBI Official Symbol
BIRC2
NCBI Official Synonym Symbols
API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1
NCBI Protein Information
baculoviral IAP repeat-containing protein 2
UniProt Protein Name
Baculoviral IAP repeat-containing protein 2
UniProt Gene Name
BIRC2
UniProt Synonym Gene Names
API1; IAP2; MIHB; RNF48; IAP-2; hIAP-2; hIAP2
UniProt Entry Name
BIRC2_HUMAN

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Product Notes

The BIRC2 birc2 (Catalog #AAA288618) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 216-244. The BIRC2 Antibody (Center) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's BIRC2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the BIRC2 birc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BIRC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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