WB (Western Blot)
(Detection of human BLOC1S3 by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-BLOC1S3 antibody AAA212810 (lot AAA212810-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
Rabbit anti-Human BLOC1S3 Polyclonal Antibody | anti-BLOC1S3 antibody
Rabbit anti-BLOC1S3 Antibody, Affinity Purified
Gene Names
BLOC1S3; RP; HPS8; BLOS3
Reactivity
Human
Applications
Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
BLOC1S3, Antibody; Rabbit anti-BLOC1S3 Antibody, Affinity Purified; BLOS3; RP; HPS8; biogenesis of lysosome-related organelles complex-1, subunit 3; biogenesis of lysosome-related organelles complex 1 subunit 3; reduced pigmentation, mouse, homolog of; BLOC-1 subunit 3; Biogenesis of lysosome-related organelles complex 1 subunit 3; biogenesis of lysosomal organelles complex 1 subunit 3; anti-BLOC1S3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-BLOC1S3 antibody
IP (Immunoprecipitation), WB (Western Blot)
Immunogen
Between 1 and 50
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human BLOC1S3 by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-BLOC1S3 antibody AAA212810 (lot AAA212810-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
WB (Western Blot)
(Detection of human BLOC1S3 by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-BLOC1S3 antibody AAA212810 (lot AAA212810-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
IP (Immunoprecipitation)
(Detection of human BLOC1S3 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-BLOC1S3 antibody AAA212810 (lot AAA212810-1) used for IP at 6 ug per reaction. BLOC1S3 was also immunoprecipitated by rabbit anti-BLOC1S3 antibody BL17617. For blotting immunoprecipitated BLOC1S3, AAA212810 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
IP (Immunoprecipitation)
(Detection of human BLOC1S3 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-BLOC1S3 antibody AAA212810 (lot AAA212810-1) used for IP at 6 ug per reaction. BLOC1S3 was also immunoprecipitated by rabbit anti-BLOC1S3 antibody BL17617. For blotting immunoprecipitated BLOC1S3, AAA212810 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
Related Product Information for anti-BLOC1S3 antibody
BLOC1S3 is a component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. It plays a role in intracellular vesicle trafficking [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6QNY0].
Product Categories/Family for anti-BLOC1S3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,256 Da
NCBI Official Full Name
biogenesis of lysosome-related organelles complex 1 subunit 3
NCBI Official Synonym Full Names
biogenesis of lysosomal organelles complex-1, subunit 3
NCBI Official Symbol
BLOC1S3
NCBI Official Synonym Symbols
RP; HPS8; BLOS3
NCBI Protein Information
biogenesis of lysosome-related organelles complex 1 subunit 3; BLOC-1 subunit 3; reduced pigmentation, mouse, homolog of; biogenesis of lysosome-related organelles complex-1, subunit 3
UniProt Protein Name
Biogenesis of lysosome-related organelles complex 1 subunit 3
UniProt Gene Name
BLOC1S3
UniProt Synonym Gene Names
BLOS3; BLOC-1 subunit 3
UniProt Entry Name
BL1S3_HUMAN
Similar Products
Product Notes
The BLOC1S3 bloc1s3 (Catalog #AAA212810) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-BLOC1S3 Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BLOC1S3 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the BLOC1S3 bloc1s3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BLOC1S3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.