IF (Immunofluorescence)
(Immunofluorescence: use at 10ug/ml. Detection of BNIP3 in formalin-fixed NIH 3T3 cells at 10ug/ml. DAPI (blue) nuclear stain, Texas red actin stain, and FITC (green) BNIP3 stain.)
Rabbit BNIP3 Polyclonal Antibody | anti-BNIP3 antibody
BNIP3 Polyclonal Antibody
Gene Names
BNIP3; NIP3
Applications
Immunoblot, Western Blot
Synonyms
BNIP3, Antibody; BNIP3 Polyclonal Antibody; anti-BNIP3 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
This antibody recognizes human and mouse BNIP3.
Form/Format
100ug (1mg/ml) peptide affinity-purified antibody in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Sequence Length
259
Applicable Applications for anti-BNIP3 antibody
IB (Immunoblot)
Immunogen
Synthetic peptide corresponding to amino acids at the C-terminus of human BNIP3.
Preparation and Storage
This antibody is stable for at least one (1) year at-20 degree C.
IF (Immunofluorescence)
(Immunofluorescence: use at 10ug/ml. Detection of BNIP3 in formalin-fixed NIH 3T3 cells at 10ug/ml. DAPI (blue) nuclear stain, Texas red actin stain, and FITC (green) BNIP3 stain.)
IF (Immunofluorescence)
(Immunofluorescence: use at 10ug/ml. Detection of BNIP3 in formalin-fixed NIH 3T3 cells at 10ug/ml. DAPI (blue) nuclear stain, Texas red actin stain, and FITC (green) BNIP3 stain.)
Application Data
(Detection of BNIP3 and complexed BNIP3 in mouse kidney lysate at 1ug/ml.)
Application Data
(Detection of BNIP3 and complexed BNIP3 in mouse kidney lysate at 1ug/ml.)
Application Data
(Detection of BNIP3 in HeLa (left) and 293T (right) cell lysates at 1ug/ml)
Application Data
(Detection of BNIP3 in HeLa (left) and 293T (right) cell lysates at 1ug/ml)
Related Product Information for anti-BNIP3 antibody
BNIP3 is a member of the apoptotic Bcl-2 protein family that is involved in both necrosis and apoptosis. Humans and other animals, as well as lower eukaryotes, encode several BNIP3 paralogues including human BNIP3L which induces apoptosis by interacting with viral and cellular anti-apoptosis proteins. BNIP3 interacts with the E1B 19kDa protein, which is responsible for the protection of virally induced cell death, as well as with E1B-like sequences of BCL2 which is also an apoptotic protector. The BNIP3 gene contains a BH3 domain and a transmembrane domain that have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by the BNIP3 gene is known to induce apoptosis, even in the presence of BCL2.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,832 Da
NCBI Official Full Name
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
NCBI Official Synonym Full Names
BCL2 interacting protein 3
NCBI Official Symbol
BNIP3
NCBI Official Synonym Symbols
NIP3
NCBI Protein Information
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
UniProt Protein Name
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
UniProt Gene Name
BNIP3
UniProt Synonym Gene Names
NIP3
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Product Notes
The BNIP3 bnip3 (Catalog #AAA47852) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BNIP3 can be used in a range of immunoassay formats including, but not limited to, IB (Immunoblot). Researchers should empirically determine the suitability of the BNIP3 bnip3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BNIP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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