IF (Immunofluorescence)
(Immunofluorescence of BTLA in human small intestine tissue with BTLA antibody at 20 μg/mL.)
Rabbit anti-Human BTLA Polyclonal Antibody | anti-BTLA antibody
BTLA Antibody
Gene Names
BTLA; BTLA1; CD272
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
BTLA Antibody is affinity chromatography purified via peptide column.
Synonyms
BTLA, Antibody; BTLA Antibody; BTLA Antibody : BTLA1; CD272; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; B and T lymphocyte associated; anti-BTLA antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
BTLA antibody is human specific. At least two isoforms of BTLA are known to exist.
Purity/Purification
BTLA Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
289
Applicable Applications for anti-BTLA antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
BTLA antibody was raised against a 17 amino acid peptide near the center of human BTLA.
Buffer
BTLA Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
BTLA antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of BTLA in human small intestine tissue with BTLA antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of BTLA in human small intestine tissue with BTLA antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of BTLA in human small intestine tissue with BTLA antibody at 2.5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of BTLA in human small intestine tissue with BTLA antibody at 2.5 μg/mL.)
WB (Western Blot)
(Western blot analysis of BTLA in Jurkat cell lysate at (A) 1 and (B) 2 μg/ml.)
WB (Western Blot)
(Western blot analysis of BTLA in Jurkat cell lysate at (A) 1 and (B) 2 μg/ml.)
Related Product Information for anti-BTLA antibody
The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 32 kDa
Observed: 40kDa
Observed: 40kDa
NCBI Official Full Name
B- and T-lymphocyte attenuator isoform 1
NCBI Official Synonym Full Names
B and T lymphocyte associated
NCBI Official Symbol
BTLA
NCBI Official Synonym Symbols
BTLA1; CD272
NCBI Protein Information
B- and T-lymphocyte attenuator; B and T lymphocyte attenuator; B- and T-lymphocyte-associated protein
UniProt Protein Name
B- and T-lymphocyte attenuator
UniProt Gene Name
BTLA
UniProt Entry Name
BTLA_HUMAN
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Product Notes
The BTLA btla (Catalog #AAA40608) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BTLA Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BTLA can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the BTLA btla for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BTLA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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