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product-image-AAA76736_AD13.jpg Application Data

Rabbit c-Fos Polyclonal Antibody | anti-c-Fos antibody

c-Fos

Gene Names
FOS; p55; AP-1; C-FOS
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, Immunocytochemistry
Synonyms
c-Fos, Antibody; c-Fos; anti-c-Fos antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Form/Format
Liquid. Affinity purified antibody at 1mg/mL in 50% PBS, 50%glycerol, plus 5mM NaN3
Applicable Applications for anti-c-Fos antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ICC (Immunocytochemistry)
Immunogen
Full length recombinant human protein expressed in and purified from E coli.
Preparation and Storage
Antibody can also be aliquotted and stored frozen at -20 degree C in a manual defrost freezer for sixmonths without detectable loss of activity. The antibody can be stored at 2 degree - 8 degree C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Application Data

product-image-AAA76736_AD13.jpg Application Data

IF (Immunofluorescence)

(Immunofluorescent analysis of HeLa cells stained with rabbit pAb to c-FOS, AAA76736, dilution 1:2,000 in red, and mouse mAb to tubulin in green. The blue is DAPI staining of nuclear DNA.)

product-image-AAA76736_IF15.jpg IF (Immunofluorescence) (Immunofluorescent analysis of HeLa cells stained with rabbit pAb to c-FOS, AAA76736, dilution 1:2,000 in red, and mouse mAb to tubulin in green. The blue is DAPI staining of nuclear DNA.)
Related Product Information for anti-c-Fos antibody
The FOS gene and protein were originally identified as the transforming element in a viral oncogene. The transforming protein was named v-FOS, for viral FOS, and the normal cellular non-transforming proto-oncogene was called c-FOS, for cellular FOS The c-FOS protein is a normal gene acting as an on/off switch controlling the expression of many other genes. Since c-FOS expression is induced in neurons which are rapidly firing action potentials, appropriate c-Fos antibodies can be used to identify activated neurons in tissues.

This was made against recombinant full length human c-FOS expressed in and purified from E coli. It can be used to identify activated cells in cell culture and in sections and to follow c-FOS expression in western blots of cell and tissue homogenates.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,695 Da
NCBI Official Full Name
proto-oncogene c-Fos
NCBI Official Synonym Full Names
FBJ murine osteosarcoma viral oncogene homolog
NCBI Official Symbol
FOS
NCBI Official Synonym Symbols
p55; AP-1; C-FOS
NCBI Protein Information
proto-oncogene c-Fos; activator protein 1; cellular oncogene c-fos; G0/G1 switch regulatory protein 7; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS)
UniProt Protein Name
Proto-oncogene c-Fos
UniProt Gene Name
FOS
UniProt Synonym Gene Names
G0S7
UniProt Entry Name
FOS_HUMAN

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Product Notes

The c-Fos fos (Catalog #AAA76736) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The c-Fos reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's c-Fos can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ICC (Immunocytochemistry). Researchers should empirically determine the suitability of the c-Fos fos for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "c-Fos, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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