Rabbit anti-Human C7 Polyclonal Antibody | anti-C7 antibody

C7 Polyclonal Antibody

Cat. Num. AAA173710

• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: Affinity Purification
• Synonyms: C7, Antibody; C7 Polyclonal Antibody; C7; Complement component C7; anti-C7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Concentration: 1mg/mL (varies by lot)
• Sequence Length: 843

• Applicable Applications for anti-C7 antibody: ELISA, IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Synthesized peptide derived from the N-terminal region of human C7.
• Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze / thaw cycles.

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded Human liver tissue using C7 Polyclonal Antibody at dilution of 1:200.)

WB (Western Blot)

(Western Blot analysis of Hela cells using C7 Polyclonal Antibody at dilution of 1:500.)

Related Product Information for anti-C7 antibody

This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. C7 (Complement C7) is a Protein Coding gene. Diseases associated with C7 include C7 Deficiency and Immunodeficiency Due To A Late Component Of Complement Deficiency. Among its related pathways are Complement Pathway and Innate Immune System. An important paralog of this gene is C6.

NCBI and Uniprot Product Information

• NCBI GI #: 45580688
• NCBI GeneID: 730
• NCBI Accession #: NP_000578.2
• NCBI GenBank Nucleotide #: NM_000587.3
• UniProt Accession #: P10643; Q6P3T5; Q92489
• Molecular Weight: Calculated Molecular Weight: 94kDa; Observed Molecular Weight: 93kDa
• NCBI Official Full Name: complement component C7
• NCBI Official Synonym Full Names: complement C7
• NCBI Official Symbol: C7
• NCBI Protein Information: complement component C7
• UniProt Protein Name: Complement component C7
• UniProt Gene Name: C7