FCM/FACS (Flow Cytometry)
(CACNA2D4 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit anti-Human CACNA2D4 Polyclonal Antibody | anti-CACNA2D4 antibody
CACNA2D4 Antibody (N-term)
Gene Names
CACNA2D4; RCD4
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CACNA2D4, Antibody; CACNA2D4 Antibody (N-term); Voltage-dependent calcium channel subunit alpha-2/delta-4; Voltage-gated calcium channel subunit alpha-2/delta-4; Voltage-dependent calcium channel subunit alpha-2-4; Voltage-dependent calcium channel subunit delta-4; CACNA2D4; anti-CACNA2D4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CACNA2D4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human CACNA2D4.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
89-118
Sequence Length
1137
Applicable Applications for anti-CACNA2D4 antibody
FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(CACNA2D4 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(CACNA2D4 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
WB (Western Blot)
(CACNA2D4 Antibody (N-term) western blot analysis in K562 cell line lysates (15ug/lane).This demonstrates the CACNA2D4 antibody detected the CACNA2D4 protein (arrow).)
WB (Western Blot)
(CACNA2D4 Antibody (N-term) western blot analysis in K562 cell line lysates (15ug/lane).This demonstrates the CACNA2D4 antibody detected the CACNA2D4 protein (arrow).)
Related Product Information for anti-CACNA2D4 antibody
CACNA2D4 is a member of the alpha-2/delta subunit
family, a protein in the voltage-dependent calcium channel complex.
Calcium channels mediate the influx of calcium ions into the cell
upon membrane polarization and consist of a complex of alpha-1,
alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various
versions of each of these subunits exist, either expressed from
similar genes or the result of alternative splicing. Research on a
highly similar protein in rabbit suggests the protein described in
this record is cleaved into alpha-2 and delta subunits. Alternate
transcriptional splice variants of this gene have been observed but
have not been thoroughly characterized.
family, a protein in the voltage-dependent calcium channel complex.
Calcium channels mediate the influx of calcium ions into the cell
upon membrane polarization and consist of a complex of alpha-1,
alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various
versions of each of these subunits exist, either expressed from
similar genes or the result of alternative splicing. Research on a
highly similar protein in rabbit suggests the protein described in
this record is cleaved into alpha-2 and delta subunits. Alternate
transcriptional splice variants of this gene have been observed but
have not been thoroughly characterized.
Product Categories/Family for anti-CACNA2D4 antibody
References
Wycisk, K.A., et al. Am. J. Hum. Genet. 79(5):973-977(2006)
Qin, N., et al. Mol. Pharmacol. 62(3):485-496(2002)
Qin, N., et al. Mol. Pharmacol. 62(3):485-496(2002)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
127938
NCBI Official Full Name
voltage-dependent calcium channel subunit alpha-2/delta-4
NCBI Official Synonym Full Names
calcium channel, voltage-dependent, alpha 2/delta subunit 4
NCBI Official Symbol
CACNA2D4
NCBI Official Synonym Symbols
RCD4
NCBI Protein Information
voltage-dependent calcium channel subunit alpha-2/delta-4
UniProt Protein Name
Voltage-dependent calcium channel subunit alpha-2/delta-4
UniProt Gene Name
CACNA2D4
UniProt Entry Name
CA2D4_HUMAN
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Product Notes
The CACNA2D4 cacna2d4 (Catalog #AAA288049) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 89-118. The CACNA2D4 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CACNA2D4 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CACNA2D4 cacna2d4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CACNA2D4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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