IHC (Immunohistochemistry)
(Immunohistochemistry analysis: Vibratome (70 um) sections of rat spinal cord immunostained with sheep polyclonal antiserum to CGRP at a dilution of 1:1000. Negative images of fluorescence detection procedure (Alexa488 conjugated secondary antibody). Micrograph courtesy of Professor Andrew Todd (University of Glasgow).)
Sheep Calcitonin gene related peptide Polyclonal Antibody | anti-CGRP antibody
Calcitonin gene related peptide polyclonal antibody
Gene Names
Calca; CAL6; CGRP; Cal1; Calc; RATCAL6; calcitonin
Reactivity
Human, Mouse, Rat, Rabbit
Applications
Immunohistochemistry
Purity
Ammonium sulphate precipitation.
Synonyms
Calcitonin gene related peptide, Antibody; Calcitonin gene related peptide polyclonal antibody; CGRP; anti-CGRP antibody
Host
Sheep
Reactivity
Human, Mouse, Rat, Rabbit
Clonality
Polyclonal
Purity/Purification
Ammonium sulphate precipitation.
Form/Format
Liquid. In PBS containing 0.1% sodium azide.
Applicable Applications for anti-CGRP antibody
IHC (Immunohistochemistry)
Source
Purified from sheep serum
Immunogen
Synthetic peptide corresponding to a portion of rat alpha -calcitonin gene-related peptide (CGRP).
Cross reactivity
Likely to react with other mammalien species (based on homology, not tested).
Preparation and Storage
Long term storage: -20°C
Avoid freeze/thaw cycles.
Avoid freeze/thaw cycles.
IHC (Immunohistochemistry)
(Immunohistochemistry analysis: Vibratome (70 um) sections of rat spinal cord immunostained with sheep polyclonal antiserum to CGRP at a dilution of 1:1000. Negative images of fluorescence detection procedure (Alexa488 conjugated secondary antibody). Micrograph courtesy of Professor Andrew Todd (University of Glasgow).)
IHC (Immunohistochemistry)
(Immunohistochemistry analysis: Vibratome (70 um) sections of rat spinal cord immunostained with sheep polyclonal antiserum to CGRP at a dilution of 1:1000. Negative images of fluorescence detection procedure (Alexa488 conjugated secondary antibody). Micrograph courtesy of Professor Andrew Todd (University of Glasgow).)
Related Product Information for anti-CGRP antibody
Calcitonin gene-related peptide (CGRP) is a 37-amino acid disulphide-bridged sensory neuropeptide present in the central and peripheral nervous systems of many animal species. Two forms of CGRP ( alpha and beta ) have been identified from both rat and human, and the sequence of chicken CGRP has also been reported, showing striking structural similarity to the mammalian forms. CGRP is abundant in perivascular sensory neurons and is known to be a potent vasodilator. Recent work supports the role of CGRP in mediating skin vasodilatation and differential mesenteric artery vasorelaxation, as well as serving as an endogenous myocardial protective substance with a possible involvement in the inhibition of human platelet aggregation. CGRP is frequently co-localised with Substance P and immunoelectron microscopic observations have shown that the peptides are co-stored in single secretory granules both in sensory neurons and in thyroid C-cells. There are many hundreds of reports in the scientific literature describing the localisation and co-existence of CGRP with other transmitter molecules in a vast array of mammalian and non-mammalian species.
Product Categories/Family for anti-CGRP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Calcitonin gene-related peptide 1
NCBI Official Synonym Full Names
calcitonin-related polypeptide alpha
NCBI Official Symbol
Calca
NCBI Official Synonym Symbols
CAL6; CGRP; Cal1; Calc; RATCAL6; calcitonin
NCBI Protein Information
calcitonin gene-related peptide 1
UniProt Protein Name
Calcitonin gene-related peptide 1
UniProt Gene Name
Calca
UniProt Synonym Gene Names
Calc; CGRP-I
UniProt Entry Name
CALCA_RAT
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Product Notes
The CGRP calca (Catalog #AAA76999) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The Calcitonin gene related peptide polyclonal antibody reacts with Human, Mouse, Rat, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's Calcitonin gene related peptide can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CGRP calca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calcitonin gene related peptide, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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