IHC (Immunohiostchemistry)
(Anti-CaMKK antibody, AAA45107, IHC(P)IHC(P): Rat Brain Tissue)
Rabbit CaMKK Polyclonal Antibody | anti-CAMKK1 antibody
Anti-CaMKK antibody
Gene Names
Camkk1; Camkk; AI846603; CaMKKalpha
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
CaMKK, Antibody; Anti-CaMKK antibody; Calcium/calmodulin-dependent protein kinase kinase 1(CaM-KK 1/CaM-kinase kinase 1/CaMKK 1); calcium/calmodulin-dependent protein kinase kinase 1, alpha; Ca2+/calmodulin-dependent protein kinase kinase alpha antibody; Calcium/calmodulin dependent protein kinase kinase antibody; Calcium/calmodulin dependent protein kinase kinase 1 alpha antibody; Calcium/calmodulin dependent protein kinase kinase 1 antibody; Calcium/calmodulin dependent protein kinase kinase alpha antibody; Calcium/calmodulin-dependent protein kinase kinase 1 antibody; Calcium/calmodulin-dependent protein kinase kinase alpha antibody; CaM kinase kinase alpha antibody; CaM-kinase IV kinase antibody; CaM-kinase kinase 1 antibody; CaM-kinase kinase alpha antibody; CaM-KK 1 antibody; CaM-KK alpha antibody; CaMKK 1 antibody; CaMKK alpha antibody; CAMKK alpha protein antibody; CaMKK antibody; CAMKK1 antibody; CAMKKA antibody; DKFZp761M0423 antibody; KKCC1_HUMAN antibody; MGC34095 antibody; OTTMUSP00000006419 antibody; anti-CAMKK1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
505
Applicable Applications for anti-CAMKK1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of mouse CaMKK (10-31aa QDPRAELVDRVAAINVAHLEEA), different from the related human sequence by three amino acids, and from the related rat sequence by two amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-CaMKK antibody, AAA45107, IHC(P)IHC(P): Rat Brain Tissue)
IHC (Immunohiostchemistry)
(Anti-CaMKK antibody, AAA45107, IHC(P)IHC(P): Rat Brain Tissue)
WB (Western Blot)
(Anti-CaMKK antibody, AAA45107, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Brain Tissue LysateLane 3: Mouse Brain Tissue LysateLane 4: Mouse Brain Tissue Lysate)
WB (Western Blot)
(Anti-CaMKK antibody, AAA45107, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Brain Tissue LysateLane 3: Mouse Brain Tissue LysateLane 4: Mouse Brain Tissue Lysate)
Related Product Information for anti-CAMKK1 antibody
Description: Rabbit IgG polyclonal antibody for Calcium/calmodulin-dependent protein kinase kinase 1(CAMKK1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: CAMKK1, Calcium/calmodulin-dependent protein kinase kinase 1 is an enzyme that in humans is encoded by the CAMKK1 gene. The CAMKK1 gene is mapped to chromosome 17. The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent(CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene.Camkk1binds calmodulin and activated Camk4 with a 6-fold increase in total activity and a 100-fold increase in Camk4 Ca(2+)-independent activity. Camkk1 catalyzed a 10-fold increase in the total activity of Camk1 and had no effect on Camk2. Cotransfection of COS-7 cells with Camkk1 and Camk4 resulted in a 14-fold increase in CRE-binding protein-dependent transcription compared with Camk4 alone, suggesting that Camkk1 enhances Camk4-mediated transcriptional regulation.
Background: CAMKK1, Calcium/calmodulin-dependent protein kinase kinase 1 is an enzyme that in humans is encoded by the CAMKK1 gene. The CAMKK1 gene is mapped to chromosome 17. The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent(CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene.Camkk1binds calmodulin and activated Camk4 with a 6-fold increase in total activity and a 100-fold increase in Camk4 Ca(2+)-independent activity. Camkk1 catalyzed a 10-fold increase in the total activity of Camk1 and had no effect on Camk2. Cotransfection of COS-7 cells with Camkk1 and Camk4 resulted in a 14-fold increase in CRE-binding protein-dependent transcription compared with Camk4 alone, suggesting that Camkk1 enhances Camk4-mediated transcriptional regulation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
55,838 Da
NCBI Official Full Name
Calcium/calmodulin-dependent protein kinase kinase 1
NCBI Official Synonym Full Names
calcium/calmodulin-dependent protein kinase kinase 1, alpha
NCBI Official Symbol
Camkk1
NCBI Official Synonym Symbols
Camkk; AI846603; CaMKKalpha
NCBI Protein Information
calcium/calmodulin-dependent protein kinase kinase 1; caMKK 1; caM-KK 1; caMKK alpha; caM-KK alpha; caM-kinase kinase 1; caM-kinase IV kinase; caM-kinase kinase alpha; calcium calmodulin dependent protein kinase kinase alpha; calcium/calmodulin-dependent protein kinase kinase alpha
UniProt Protein Name
Calcium/calmodulin-dependent protein kinase kinase 1
UniProt Gene Name
Camkk1
UniProt Synonym Gene Names
Camkk; CaM-KK 1; CaM-kinase kinase 1; CaMKK 1; CaM-KK alpha; CaM-kinase kinase alpha; CaMKK alpha
UniProt Entry Name
KKCC1_MOUSE
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Product Notes
The CAMKK1 camkk1 (Catalog #AAA45107) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CaMKK antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CaMKK can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CAMKK1 camkk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CaMKK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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