IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human colon using CASC5 at dilution of 1:100 (40x lens).)
Rabbit anti-Human, Rat CASC5 Polyclonal Antibody | anti-CASC5 antibody
CASC5 Rabbit Polyclonal Antibody
Gene Names
CASC5; D40; CT29; KNL1; Spc7; hKNL-1; AF15Q14; PPP1R55; hSpc105
Reactivity
Human, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
CASC5, Antibody; CASC5 Rabbit Polyclonal Antibody; AF15Q14; CASC5; CT29; D40; MCPH4; PPP1R55; Spc7; hKNL-1; hSpc105; KNL1; anti-CASC5 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Applicable Applications for anti-CASC5 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant fusion protein of human CASC5 (NP_733468.3).
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human colon using CASC5 at dilution of 1:100 (40x lens).)
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human colon using CASC5 at dilution of 1:100 (40x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded rat testis using CASC5 at dilution of 1:100 (40x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded rat testis using CASC5 at dilution of 1:100 (40x lens).)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using CASC5 at 1:3000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using CASC5 at 1:3000 dilution.)
Related Product Information for anti-CASC5 antibody
The protein encoded by this gene is a component of the multiprotein assembly that is required for creation of kinetochore-microtubule attachments and chromosome segregation. The encoded protein functions as a scaffold for proteins that influence the spindle assembly checkpoint during the eukaryotic cell cycle and it interacts with at least five different kinetochore proteins and two checkpoint kinases. In adults, this gene is predominantly expressed in normal testes, various cancer cell lines and primary tumors from other tissues and is ubiquitously expressed in fetal tissues. This gene was originally identified as a fusion partner with the mixed-lineage leukemia (MLL) gene in t(11;15)(q23;q14). Mutations in this gene cause autosomal recessive primary microcephaly-4 (MCPH4). Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described but their biological validity has not been confirmed.
Product Categories/Family for anti-CASC5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
265,391 Da
NCBI Official Full Name
protein CASC5 isoform 2
NCBI Official Synonym Full Names
cancer susceptibility candidate 5
NCBI Official Symbol
CASC5
NCBI Official Synonym Symbols
D40; CT29; KNL1; Spc7; hKNL-1; AF15Q14; PPP1R55; hSpc105
NCBI Protein Information
protein CASC5; cancer/testis antigen 29; kinetochore null 1 homolog; kinetochore-null protein 1; blinkin, bub-linking kinetochore protein; protein phosphatase 1, regulatory subunit 55; ALL1-fused gene from chromosome 15q14 protein; cancer susceptibility c
UniProt Protein Name
Protein CASC5
UniProt Gene Name
CASC5
UniProt Synonym Gene Names
KIAA1570; KNL1; AF15q14; Blinkin; CT29
UniProt Entry Name
CASC5_HUMAN
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Product Notes
The CASC5 casc5 (Catalog #AAA313368) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CASC5 Rabbit Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CASC5 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CASC5 casc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASC5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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