WB (Western Blot)
(Western blot analysis of CASK (Center K227) in HL-60 cell line lysates (35ug/lane).CASK (arrow) was detected using the purified Pab.)
Rabbit CASK Polyclonal Antibody | anti-CASK antibody
CASK Antibody (Center K227)
Gene Names
CASK; CMG; FGS4; LIN2; TNRC8; CAGH39; CAMGUK; MICPCH; MRXSNA
Reactivity
Human; Predicted Reactivity: Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
CASK, Antibody; CASK Antibody (Center K227); Peripheral plasma membrane protein CASK; hCASK; Calcium/calmodulin-dependent serine protein kinase; Protein lin-2 homolog; CASK; LIN2; anti-CASK antibody
Host
Rabbit
Reactivity
Human; Predicted Reactivity: Mouse, Rat
Clonality
Polyclonal
Isotype
Ig
Specificity
This CASK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-291 amino acids from the Central region of human CASK.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Sequence Length
898
Applicable Applications for anti-CASK antibody
ELISA, WB (Western Blot)
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Cellular Location
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein.
Tissue Location
Ubiquitous. Expression is significantly greater in brain relative to kidney, lung, and liver and in fetal brain and kidney relative to lung and liver.
Antigen Region
262-291 aa
Antigen Type
Synthetic Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of CASK (Center K227) in HL-60 cell line lysates (35ug/lane).CASK (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of CASK (Center K227) in HL-60 cell line lysates (35ug/lane).CASK (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of CASK (Center K227) in Hela cell line lysates (35ug/lane).CASK (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of CASK (Center K227) in Hela cell line lysates (35ug/lane).CASK (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Anti-CASK (Center K227) Antibody at 1:1000 dilution + SH-SY5Y whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 105 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(Anti-CASK (Center K227) Antibody at 1:1000 dilution + SH-SY5Y whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 105 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-CASK antibody
Description: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).
Background: Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4. 1.
Background: Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4. 1.
Product Categories/Family for anti-CASK antibody
References
Stevenson, D., et al., Mamm. Genome 11 (10):934-937 (2000). Cohen, A.R., et al., J. Cell Biol. 142 (1):129-138 (1998). Daniels, D.L., et al., Nat. Struct. Biol. 5 (4):317-325 (1998).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
105123 Da
NCBI Official Full Name
peripheral plasma membrane protein CASK isoform 2
NCBI Official Synonym Full Names
calcium/calmodulin dependent serine protein kinase
NCBI Official Symbol
CASK
NCBI Official Synonym Symbols
CMG; FGS4; LIN2; TNRC8; CAGH39; CAMGUK; MICPCH; MRXSNA
NCBI Protein Information
peripheral plasma membrane protein CASK
UniProt Protein Name
Peripheral plasma membrane protein CASK
UniProt Gene Name
CASK
UniProt Synonym Gene Names
LIN2; hCASK
UniProt Entry Name
CSKP_HUMAN
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Product Notes
The CASK cask (Catalog #AAA290697) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CASK Antibody (Center K227) reacts with Human; Predicted Reactivity: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CASK can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CASK cask for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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