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IHC (Immunohistochemistry)
(Immunohistochemistry analysis of paraffin-embedded human liver cancer using CASP1 Polyclonal Antibody at dilution of 1:300.)
Rabbit CASP1 Polyclonal Antibody | anti-CASP1 antibody
CASP1 Polyclonal Antibody
Gene Names
CASP1; ICE; P45; IL1BC
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Purification
Synonyms
CASP1, Antibody; CASP1 Polyclonal Antibody; CASP-1; CASP1; Caspase 1; Caspase-1 subunit p10; ICE; IL-1 beta-converting enzyme; IL-1BC; IL1 beta converting enzyme; IL1B convertase; Interleukin 1 beta convertase; Interleukin 1B converting enzyme; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45; anti-CASP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
Concentration
1.2 mg/mL (varies by lot)
Sequence Length
383
Applicable Applications for anti-CASP1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant protein corresponding to Mouse Caspase1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IHC (Immunohistochemistry)
(Immunohistochemistry analysis of paraffin-embedded human liver cancer using CASP1 Polyclonal Antibody at dilution of 1:300.)
IHC (Immunohistochemistry)
(Immunohistochemistry analysis of paraffin-embedded human liver cancer using CASP1 Polyclonal Antibody at dilution of 1:300.)
IHC (Immunohistochemisry)
(Immunohistochemistry analysis of paraffin-embedded human lung cancer using CASP1 Polyclonal Antibody at dilution of 1:300.)
IHC (Immunohistochemisry)
(Immunohistochemistry analysis of paraffin-embedded human lung cancer using CASP1 Polyclonal Antibody at dilution of 1:300.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human tonsil using CASP1 Polyclonal Antibody at dilution of 1:300.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human tonsil using CASP1 Polyclonal Antibody at dilution of 1:300.)
WB (Western Blot)
(Western Blot analysis of various samples using CASP1 Polyclonal Antibody at dilution of 1:1000.)
WB (Western Blot)
(Western Blot analysis of various samples using CASP1 Polyclonal Antibody at dilution of 1:1000.)
Related Product Information for anti-CASP1 antibody
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
Product Categories/Family for anti-CASP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 45kDa
Observed: 45-47kDa; 30kDa; 35kDa
Observed: 45-47kDa; 30kDa; 35kDa
NCBI Official Full Name
caspase-1 isoform beta
NCBI Official Synonym Full Names
caspase 1
NCBI Official Symbol
CASP1
NCBI Official Synonym Symbols
ICE; P45; IL1BC
NCBI Protein Information
caspase-1
UniProt Protein Name
Caspase-1
UniProt Gene Name
CASP1
UniProt Synonym Gene Names
IL1BC; IL1BCE; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme
Similar Products
Product Notes
The CASP1 casp1 (Catalog #AAA174536) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CASP1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CASP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CASP1 casp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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