IHC (Immunohiostchemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human pancreatic cancer tissue using 31012 (CASP1 Antibody) at dilution 1/25, on the right is treated with the fusion protein.)
Rabbit anti-Human CASP1 Polyclonal Antibody | anti-CASP1 antibody
CASP1 Antibody
Gene Names
CASP1; ICE; P45; IL1BC
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Synonyms
CASP1, Antibody; CASP1 Antibody; Caspase-1, ICE, P45, IL1BC; anti-CASP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total CASP1 protein.
Form/Format
Supplied at 0.8mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Sequence Length
1090
Applicable Applications for anti-CASP1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Recombinant Protein
Immunogen Description
Full length fusion protein
Target Name
CASP1
Preparation and Storage
Store at -20 degree C/1 year
IHC (Immunohiostchemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human pancreatic cancer tissue using 31012 (CASP1 Antibody) at dilution 1/25, on the right is treated with the fusion protein.)
IHC (Immunohiostchemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human pancreatic cancer tissue using 31012 (CASP1 Antibody) at dilution 1/25, on the right is treated with the fusion protein.)
Application Data
(Gel: 8%SDS-PAGE Lysate: 40 ug Hela cell lysate Primary antibody: 1/1000 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 30 seconds)
Application Data
(Gel: 8%SDS-PAGE Lysate: 40 ug Hela cell lysate Primary antibody: 1/1000 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 30 seconds)
Related Product Information for anti-CASP1 antibody
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
Product Categories/Family for anti-CASP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
10,417 Da
NCBI Official Full Name
Homo sapiens caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), mRNA
NCBI Official Synonym Full Names
caspase 1, apoptosis-related cysteine peptidase
NCBI Official Symbol
CASP1
NCBI Official Synonym Symbols
ICE; P45; IL1BC
NCBI Protein Information
caspase-1
UniProt Protein Name
Caspase-1
UniProt Gene Name
CASP1
UniProt Synonym Gene Names
IL1BC; IL1BCE; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme
UniProt Entry Name
CASP1_HUMAN
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Product Notes
The CASP1 casp1 (Catalog #AAA302234) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CASP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CASP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the CASP1 casp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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