IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human stomach cancer using CASP7 antibody at dilution of 1:200 (400x lens).)
Rabbit anti-Human, Mouse CASP7 Polyclonal Antibody | anti-CASP7 antibody
CASP7 Antibody
Gene Names
CASP7; MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3
Reactivity
Human, Mouse
Applications
Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
CASP7, Antibody; CASP7 Antibody; CMH-1; ICE-LAP3; MCH3; CASP7; Caspase-7; anti-CASP7 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total CASP7 protein.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
303
Applicable Applications for anti-CASP7 antibody
IP (Immunoprecipitation), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human CASP7.
Target Name
CASP7
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human stomach cancer using CASP7 antibody at dilution of 1:200 (400x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human stomach cancer using CASP7 antibody at dilution of 1:200 (400x lens).)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using CASP7 antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using CASP7 antibody.)
Related Product Information for anti-CASP7 antibody
Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis (1-4). Caspase-7, like caspase-3, is an effector caspase that is responsible for cleaving downstream substrates such as (ADP-ribose) polymerase and PARP (1,3). During apoptosis, caspase-7 is activated through proteolytic processsing by upstream caspases at Asp23, Asp198, and Asp206 to produce the mature subunits (1,3). Similar to caspases-2 and -3, caspase-7 preferentially cleaves substrates following the recognition sequence DEVD (5).
Product Categories/Family for anti-CASP7 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,614 Da
NCBI Official Full Name
caspase-7 isoform alpha
NCBI Official Synonym Full Names
caspase 7, apoptosis-related cysteine peptidase
NCBI Official Symbol
CASP7
NCBI Official Synonym Symbols
MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3
NCBI Protein Information
caspase-7
UniProt Protein Name
Caspase-7
UniProt Gene Name
CASP7
UniProt Synonym Gene Names
MCH3; CASP-7; ICE-LAP3
UniProt Entry Name
CASP7_HUMAN
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Product Notes
The CASP7 casp7 (Catalog #AAA308014) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CASP7 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CASP7 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CASP7 casp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASP7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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