IF (Immunofluorescence)
(Immunofluorescence staining of methanol-fixed BC3H1 cells showing cytoplasmic localization.)
Rabbit Caspase 1 Polyclonal Antibody | anti-Casp12 antibody
Caspase 12 Antibody
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunoprecipitation, Western Blot
Purity
Immunogen affinity purification
Synonyms
Caspase 1, Antibody; Caspase 12 Antibody; CASP 12 antibody; anti-Casp12 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Immunogen affinity purification
Form/Format
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-Casp12 antibody
IF (Immunofluorescence), IP (Immunoprecipitation), WB (Western Blot)
Preparation and Storage
Store at -20 degree C
IF (Immunofluorescence)
(Immunofluorescence staining of methanol-fixed BC3H1 cells showing cytoplasmic localization.)
IF (Immunofluorescence)
(Immunofluorescence staining of methanol-fixed BC3H1 cells showing cytoplasmic localization.)
WB (Western Blot)
(Western blot analysis of caspase-12 expression in BC3H1 (A) and UV-treated NIH/3T3 (B) whole cell lysates.)
WB (Western Blot)
(Western blot analysis of caspase-12 expression in BC3H1 (A) and UV-treated NIH/3T3 (B) whole cell lysates.)
Related Product Information for anti-Casp12 antibody
A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/caspase-1, is composed of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9, caspase-10, caspase-14, and caspase-5/caspase-12. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-5 (also designated TY or ICErelIII) can cleave its own precursor, an activity that requires the cysteine 245 residue. The mouse homolog of caspase-5 is designated caspase-12. Frameshift mutations in caspase-5 have been identified in MMP tumors of the endometrium, colon, and stomach, indicating that caspase-5 may be a new target gene in the microsatellite mutator pathway for cancer.
Product Categories/Family for anti-Casp12 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
47,854 Da
NCBI Official Full Name
caspase-12
NCBI Official Synonym Full Names
caspase 12
NCBI Official Symbol
Casp12
NCBI Protein Information
caspase-12; CASP-12
UniProt Protein Name
Caspase-12
UniProt Gene Name
Casp12
UniProt Synonym Gene Names
CASP-12
UniProt Entry Name
CASPC_MOUSE
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Product Notes
The Casp12 casp12 (Catalog #AAA312982) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Caspase 12 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Caspase 1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the Casp12 casp12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caspase 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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