IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of human spleen tissue stained with Caspase-3, pAb at 10µg/ml.)
Rabbit Caspase-3 Polyclonal Antibody | anti-CASP3 antibody
Caspase-3 polyclonal antibody
Gene Names
CASP3; CPP32; SCA-1; CPP32B
Reactivity
Human, Mouse, Rat, Bovine, Chicken, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Yeast
Applications
Western Blot, Immunohistochemistry
Purity
Protein A affinity purified.
Synonyms
Caspase-3, Antibody; Caspase-3 polyclonal antibody; anti-CASP3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine, Chicken, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Yeast
Clonality
Polyclonal
Purity/Purification
Protein A affinity purified.
Form/Format
Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Sequence Length
277
Applicable Applications for anti-CASP3 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Source Note
Purified from rabbit serum
Immunogen
Recombinant human Caspase-3 protein (full length).
Preparation and Storage
Store at -20°C for long term. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of human spleen tissue stained with Caspase-3, pAb at 10µg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of human spleen tissue stained with Caspase-3, pAb at 10µg/ml.)
WB (Western Blot)
(Western blot analysis of Caspase-3 pAb:Lane 1: MW MarkerLane 2: JurkatLane 3: Jurkat treated with staurosporineLane 4: MCF-7 (negative control)Lane 5: HeLa, (cell lysate)Lane 6: Rat SpleenLane 7: Mouse Spleen.)
WB (Western Blot)
(Western blot analysis of Caspase-3 pAb:Lane 1: MW MarkerLane 2: JurkatLane 3: Jurkat treated with staurosporineLane 4: MCF-7 (negative control)Lane 5: HeLa, (cell lysate)Lane 6: Rat SpleenLane 7: Mouse Spleen.)
Related Product Information for anti-CASP3 antibody
The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.
Product Categories/Family for anti-CASP3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Caspase-3
NCBI Official Synonym Full Names
caspase 3
NCBI Official Symbol
CASP3
NCBI Official Synonym Symbols
CPP32; SCA-1; CPP32B
NCBI Protein Information
caspase-3
UniProt Protein Name
Caspase-3
UniProt Gene Name
CASP3
UniProt Synonym Gene Names
CPP32; CASP-3; CPP-32; SCA-1
UniProt Entry Name
CASP3_HUMAN
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Product Notes
The CASP3 casp3 (Catalog #AAA77001) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Caspase-3 polyclonal antibody reacts with Human, Mouse, Rat, Bovine, Chicken, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Yeast and may cross-react with other species as described in the data sheet. AAA Biotech's Caspase-3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CASP3 casp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caspase-3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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