IHC (Immunohiostchemistry)
(Anti-Caspase-7(P11) antibody, AAA45075, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
Rabbit Caspase-7(P11) Polyclonal Antibody | anti-CASP7 antibody
Anti-Caspase-7(P11) antibody
Gene Names
CASP7; MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Caspase-7(P11), Antibody; Anti-Caspase-7(P11) antibody; Caspase-7(CASP-7); caspase 7, apoptosis-related cysteine peptidase; Apoptosis related cysteine peptidase antibody; Apoptosis Related Cysteine Protease antibody; Apoptotic protease Mch-3 antibody; Apoptotic Protease MCH3 antibody; CASP 7 antibody; CASP-7 antibody; CASP7 antibody; Caspase-7 subunit p11 antibody; Caspase7 antibody; CMH 1 antibody; CMH-1 antibody; CMH1 antibody; ICE LAP3 antibody; ICE like Apoptotic Protease 3 antibody; ICE-LAP3 antibody; ICE-like apoptotic protease 3 antibody; MCH3 antibody; anti-CASP7 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
303
Applicable Applications for anti-CASP7 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Caspase-7 (P11) (237-255aa RGSWFVQALCSILEEHGKD), different from the related mouse and rat sequences by two amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-Caspase-7(P11) antibody, AAA45075, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Caspase-7(P11) antibody, AAA45075, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
WB (Western Blot)
(Anti-Caspase-7(P11) antibody, AAA45075, Western blottingAll lanes: Anti CASP7(p11) (AAA45075) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: MCF-7 Whole Cell Lysate at 40ugLane 3: Rat Liver Tissue Lysate at 50ugLane 4: Rat Kidney Tissue Lysate at 50ugPredicted bind size: 34KDObserved bind size: 34KD)
WB (Western Blot)
(Anti-Caspase-7(P11) antibody, AAA45075, Western blottingAll lanes: Anti CASP7(p11) (AAA45075) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: MCF-7 Whole Cell Lysate at 40ugLane 3: Rat Liver Tissue Lysate at 50ugLane 4: Rat Kidney Tissue Lysate at 50ugPredicted bind size: 34KDObserved bind size: 34KD)
Related Product Information for anti-CASP7 antibody
Description: Rabbit IgG polyclonal antibody for Caspase-7(CASP7) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: CASP7, Caspase-7, apoptosis-related cysteine peptidase, is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the caspase(cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of CASP7 regulates microglia activation through a protein kinase C-delta(PRKCD)-dependent pathway.
Background: CASP7, Caspase-7, apoptosis-related cysteine peptidase, is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the caspase(cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of CASP7 regulates microglia activation through a protein kinase C-delta(PRKCD)-dependent pathway.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
31,614 Da
NCBI Official Full Name
Caspase-7
NCBI Official Synonym Full Names
caspase 7, apoptosis-related cysteine peptidase
NCBI Official Symbol
CASP7
NCBI Official Synonym Symbols
MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3
NCBI Protein Information
caspase-7; apoptotic protease MCH-3; ICE-like apoptotic protease 3; caspase 7, apoptosis-related cysteine protease
UniProt Protein Name
Caspase-7
UniProt Gene Name
CASP7
UniProt Synonym Gene Names
MCH3; CASP-7; ICE-LAP3
UniProt Entry Name
CASP7_HUMAN
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Product Notes
The CASP7 casp7 (Catalog #AAA45075) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Caspase-7(P11) antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Caspase-7(P11) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CASP7 casp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caspase-7(P11), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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