Application Data
Rabbit Caspase-8 Polyclonal Antibody | anti-CASP8 antibody
Anti-Caspase-8 Antibody
Gene Names
CASP8; caspase-8
Applications
Immunocytochemistry, Immunoblot, Western Blot
Purity
Purified by immunoaffinity chromatography
Synonyms
Caspase-8, Antibody; Anti-Caspase-8 Antibody; Anti-Caspase-8; anti-CASP8 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
This antibody recognizes human, mouse, and rat Caspase-8 (18kDa).
Purity/Purification
Purified by immunoaffinity chromatography
Form/Format
Clear Liquid
Concentration
0.1mg/mL OBS, pH7.4 (varies by lot)
Sequence Length
482
Applicable Applications for anti-CASP8 antibody
ICC (Immunocytochemistry), IB (Immunoblot)
Antigen
Synthetic peptide corresponding to 16 amino acids at the C-terminus of human Caspase-8 isoform A (accession no. NP_001219).
Preservatives
0.02% sodium azide
Positive Control
Jurkat cell lysate
Immunocytochemistry
Use at 2ug/ml.
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Application Data
Application Data
Application Data
Application Data
Related Product Information for anti-CASP8 antibody
Caspases are a family of cysteine proteases. Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex. The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain; subsequent oligomerization promotes procaspase-8 autoactivation. FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis.
Product Categories/Family for anti-CASP8 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
caspase-8
NCBI Official Synonym Full Names
caspase 8, apoptosis-related cysteine peptidase
NCBI Official Symbol
CASP8
NCBI Official Synonym Symbols
caspase-8
NCBI Protein Information
caspase-8
Similar Products
Product Notes
The CASP8 (Catalog #AAA47945) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Caspase-8 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IB (Immunoblot). Researchers should empirically determine the suitability of the CASP8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caspase-8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.