IHC (Immunohiostchemistry)
(CCDC50 Antibody (Center) (AAA289787)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCDC50 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit CCDC50 Polyclonal Antibody | anti-CCDC50 antibody
CCDC50 Antibody (Center)
Gene Names
CCDC50; YMER; C3orf6; DFNA44
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CCDC50, Antibody; CCDC50 Antibody (Center); Coiled-coil domain-containing protein 50; Protein Ymer; CCDC50; C3orf6; anti-CCDC50 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CCDC50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human CCDC50.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.45 (varies by lot)
Sequence Positions
86-114
Sequence Length
306
Applicable Applications for anti-CCDC50 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CCDC50 Antibody (Center) (AAA289787)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCDC50 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(CCDC50 Antibody (Center) (AAA289787)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCDC50 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(CCDC50 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CCDC50 antibody detected the CCDC50 protein (arrow).)
WB (Western Blot)
(CCDC50 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CCDC50 antibody detected the CCDC50 protein (arrow).)
Related Product Information for anti-CCDC50 antibody
This gene encodes a soluble, cytoplasmic,
tyrosine-phosphorylated protein with multiple ubiquitin-interacting
domains. Mutations in this gene cause nonsyndromic, postlingual,
progressive sensorineural DFNA44 hearing loss. In mouse, the
protein is expressed in the inner ear during development and
postnatal maturation and associates with microtubule-based
structures. This protein may also function as a negative regulator
of NF-kB signaling and as an effector of epidermal growth factor
(EGF)-mediated cell signaling. Alternative splicing results in
multiple transcript variants encoding distinct isoforms. [provided
by RefSeq].
tyrosine-phosphorylated protein with multiple ubiquitin-interacting
domains. Mutations in this gene cause nonsyndromic, postlingual,
progressive sensorineural DFNA44 hearing loss. In mouse, the
protein is expressed in the inner ear during development and
postnatal maturation and associates with microtubule-based
structures. This protein may also function as a negative regulator
of NF-kB signaling and as an effector of epidermal growth factor
(EGF)-mediated cell signaling. Alternative splicing results in
multiple transcript variants encoding distinct isoforms. [provided
by RefSeq].
References
Farfsing, A., et al. Leukemia 23(11):2018-2026(2009)
Kameda, H., et al. Biochem. Biophys. Res. Commun. 378(4):744-749(2009)
Bohgaki, M., et al. Biochim. Biophys. Acta 1783(5):826-837(2008)
Modamio-Hoybjor, S., et al. Am. J. Hum. Genet. 80(6):1076-1089(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Kameda, H., et al. Biochem. Biophys. Res. Commun. 378(4):744-749(2009)
Bohgaki, M., et al. Biochim. Biophys. Acta 1783(5):826-837(2008)
Modamio-Hoybjor, S., et al. Am. J. Hum. Genet. 80(6):1076-1089(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35822
NCBI Official Full Name
coiled-coil domain-containing protein 50 short isoform
NCBI Official Synonym Full Names
coiled-coil domain containing 50
NCBI Official Symbol
CCDC50
NCBI Official Synonym Symbols
YMER; C3orf6; DFNA44
NCBI Protein Information
coiled-coil domain-containing protein 50
UniProt Protein Name
Coiled-coil domain-containing protein 50
UniProt Gene Name
CCDC50
UniProt Synonym Gene Names
C3orf6
UniProt Entry Name
CCD50_HUMAN
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Product Notes
The CCDC50 ccdc50 (Catalog #AAA289787) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 86-114. The CCDC50 Antibody (Center) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's CCDC50 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CCDC50 ccdc50 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCDC50, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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